60049-45-8

Upstream product

• 60049-44-7 (R)-2-[(2R)-3c-benzoylamino-2r-(2-methyl-3-oxo-propylsulfanyl)-4-oxo-azetidin-1-yl]-3-methyl-but-3-enoic acid methyl ester 
• 102770-08-1 Cyclohexa-2,5-dienoyl-L-cysteinyl-D-valine 
• 186581-53-3 diazomethane 
• 6489-59-4 Phenyl penicillin 
• 59508-77-9 6β-benzoylamino-1β-oxo-1λ⁴-penicillanic acid methyl ester 

Downstream Products

• 60376-42-3 (6'R)-4-cyano-3',3'-dimethyl-5-phenyl-7'-oxo-1,3-dihydro-(5'tH,6'rN)-spiro[pyrrole-2,6'-(4-thia-1-aza-bicyclo[3.2.0]heptane)]-2't-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Penicillin Biosynthesis: Direct Biosynthetic Formation of Penicillin V and Penicillin G

The enzyme isopenicillin N synthetase is able to convert directly the dipeptides, phenoxyacetylcysteinylvaline and phenylacetylcysteinylvaline into penicillin V and G respectively; these are however very slow compared with substrates of the α-aminoadipoyl or adipoylcysteinylvaline type.