60053-39-6

Upstream product

• 6044-68-4 3,3-dimethoxyprop-1-ene 
• 131190-43-7 ((E)-1-Methoxy-3-phenyl-allyl)-trimethyl-silane 
• 113854-09-4 C₁₆H₁₆O₃S 
• 115476-86-3 (E)-2-Benzenesulfonyl-3-methoxy-1-phenyl-prop-2-en-1-ol 
• 4009-98-7 (methoxymethyl)triphenylphosphonium chloride 
• 122-78-1 phenylacetaldehyde 
• 108-86-1 bromobenzene 

Relevant academic research and scientific papers

Saegusa Oxidation of Enol Ethers at Extremely Low Pd-Catalyst Loadings under Ligand-free and Aqueous Conditions: Insight into the Pd(II)/Cu(II)-Catalyst System

A highly efficient and practical Pd(II)/Cu(OAc)2-catalyst system of Saegusa oxidation, which converts enol ethers to the corresponding enals with a number of diverse substrates at extremely low catalyst loadings (500 mol ppm) under ligand-free and aqueous conditions, is described. Its synthetic utility was demonstrated by large-scale applications of the catalyst system to important nature molecules. This work allows Saegusa oxidation to become a highly practical approach to preparing enals and also suggests new insight into the Pd(II)/Cu(II)-catalyst system for dehydrogenation of carbonyl compounds and decreasing Pd-catalyst loadings.

ORGANOTIN HOMOENOLATE EQUIVALENTS - ACCESS TO β-ACYL- AND β-ARYL-PROPIONALDEHYDES THROUGH HETEROSUBSTITUTED ALLYLTINS AND VINYLTINS

Although, α-ethoxycrotyltributyltin can be used as an equivalent of the homoenolate anion CH3-CHCH2CHO in reactions with acyl chlorides, the non-substituted α-ethoxyallyltributyltin could not be employed in this way. γ-Methoxyvinyltins, easily prepared by hydrostannation of propargylic ethers, are successfully employed as synthetic equivalents of the homoenolate anions -CH2CH2CHO and -CH2CH2COCH3 in reactions with acyl chlorides.A silylated γ-methoxyvinyltin, which is both a vinyltin and an allylsilane, reacts with acyl chlorides and aryl bromides as a promising equivalent of the homoenolate anion -CH2CH2CHO and tolerates a wide range of other reactive functional groups.

PREPARATION AND REACTIONS OF A VINYL CARBANION DERIVED FROM AN OXYGENATED VINYL SULPHONE

Addition of nBuLi to 1,1-dimethoxy-2-phenylsulphonylethane results in stereospecific elimination followed by in situ regiospecific metallation of the resulting vinyl sulphone.