60058-16-4 Usage
Uses
Used in Pharmaceutical Research:
4-hydroxy-1,5-naphthyridin-2(1H)-one is used as a research compound for its potential as an inhibitor of DNA and RNA polymerases, which are key enzymes in the replication and transcription processes of genetic material. This makes it a candidate for the development of new drugs targeting these enzymes.
Used in Antimicrobial Applications:
In the field of antimicrobial research, 4-hydroxy-1,5-naphthyridin-2(1H)-one is used as an antifungal and antibacterial agent. Its ability to inhibit the growth of fungi and bacteria positions it as a potential component in the development of new antimicrobial therapies, particularly in the context of increasing antibiotic resistance.
Used in Drug Development:
4-hydroxy-1,5-naphthyridin-2(1H)-one is utilized as a lead compound in drug development, where its structure can be further optimized to enhance its biological activities and therapeutic potential. 4-hydroxy-1,5-naphthyridin-2(1H)-one's properties may be harnessed to create new medications for various diseases and conditions.
Used in Chemical Synthesis:
In the chemical synthesis industry, 4-hydroxy-1,5-naphthyridin-2(1H)-one may be used as a building block or intermediate in the synthesis of more complex molecules with specific biological activities or pharmaceutical applications. Its unique structure can be a valuable component in the creation of novel chemical entities.
Check Digit Verification of cas no
The CAS Registry Mumber 60058-16-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,0,5 and 8 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 60058-16:
(7*6)+(6*0)+(5*0)+(4*5)+(3*8)+(2*1)+(1*6)=94
94 % 10 = 4
So 60058-16-4 is a valid CAS Registry Number.
60058-16-4Relevant academic research and scientific papers
INHIBITORS OF LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE (LMPTP) AND USES THEREOF
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Paragraph 00291, (2018/11/26)
Protein tyrosine phosphatases (PTPs) are key regulators of metabolism and insulin signaling. As a negative regulator of insulin signaling, the low molecular weight protein tyrosine phosphatase (LMPTP) is a target for insulin resistance and related conditions. Described herein are compounds capable of modulating the level of activity of low molecular weight protein tyrosine phosphatase (LMPTP) and compositions, and methods of using these compounds and compositions.
NEUROLOGICALLY-ACTIVE COMPOUNDS
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Page 101, (2010/02/06)
The present invention relates to neurologically-active compounds, being heterocyclic compounds having two fused 6-membered rings with a nitrogen atom at position 1 and a hydroxy or mercapto group at position 8 with at least one ring being aromatic. Also disclosed are processes for the preparation of these compounds and their use as pharmaceutical or veterinary agents, in particular for the treatment of neurological conditions, more specifically neurodegenerative conditions such as Alzheimer's disease.
