60058-22-2Relevant academic research and scientific papers
Acidic solvent-free removal of amine-protecting diphenylmethyl groups in the presence of camphorsulfonic acid
Yamagiwa, Noriyuki,Okabe, Takayuki,Suto, Yutaka,Iwasaki, Genji
, p. 1456 - 1458 (2017/11/04)
We developed novel reaction conditions for the removal of the diphenylmethyl group, which is one of the most important protecting groups for amines. The reaction was promoted by adding one equivalent of camphorsulfonic acid in aqueous media, and no acidic
Selective O-benzylation of aminoalkanols
Hu,Cassady
, p. 907 - 913 (2007/10/02)
A simple and one-step method has been developed for selective O-benzylation of aminoalkanols. Study of steric effects shows the best selectivity in adjacent 1°-OH vs 2°-CHNH2 and decreased selectivity in 2°-OH vs 1°-CH2NH2 and non adjacent aminoalkanol.
