60060-10-8 Usage
Uses
Used in Pharmaceutical Synthesis:
Ethyl 4-hydroxy-2-(2-pyridinyl)-5-pyrimidinecarboxylate is used as an intermediate in the synthesis of pharmaceuticals. Its unique structure allows it to be incorporated into various drug molecules, potentially leading to the development of new medications with improved efficacy and reduced side effects.
Used in Agrochemical Synthesis:
In the agrochemical industry, ethyl 4-hydroxy-2-(2-pyridinyl)-5-pyrimidinecarboxylate is used as a building block for the development of new agrochemicals. Its incorporation into these compounds can enhance their effectiveness in pest control and crop protection, contributing to increased agricultural productivity.
Used in Biological Research:
Ethyl 4-hydroxy-2-(2-pyridinyl)-5-pyrimidinecarboxylate may possess potential biological activities and medicinal properties. Researchers are exploring its interactions with biological systems to understand its potential applications in drug discovery and development. Further studies are needed to fully elucidate its effects and establish its therapeutic potential.
Check Digit Verification of cas no
The CAS Registry Mumber 60060-10-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,0,6 and 0 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 60060-10:
(7*6)+(6*0)+(5*0)+(4*6)+(3*0)+(2*1)+(1*0)=68
68 % 10 = 8
So 60060-10-8 is a valid CAS Registry Number.
60060-10-8Relevant academic research and scientific papers
Discovery of N-[Bis(4-methoxyphenyl)methyl]-4-hydroxy-2-(pyridazin-3-yl)pyrimidine-5-carboxamide (MK-8617), an Orally Active Pan-Inhibitor of Hypoxia-Inducible Factor Prolyl Hydroxylase 1-3 (HIF PHD1-3) for the Treatment of Anemia
Debenham, John S.,Madsen-Duggan, Christina,Clements, Matthew J.,Walsh, Thomas F.,Kuethe, Jeffrey T.,Reibarkh, Mikhail,Salowe, Scott P.,Sonatore, Lisa M.,Hajdu, Richard,Milligan, James A.,Visco, Denise M.,Zhou, Dan,Lingham, Russell B.,Stickens, Dominique,Demartino, Julie A.,Tong, Xinchun,Wolff, Michael,Pang, Jianmei,Miller, Randy R.,Sherer, Edward C.,Hale, Jeffrey J.
, p. 11039 - 11049 (2016/12/30)
The discovery of novel 4-hydroxy-2-(heterocyclic)pyrimidine-5-carboxamide inhibitors of hypoxia-inducible factor (HIF) prolyl hydroxylases (PHD) is described. These are potent, selective, orally bioavailable across several species, and active in stimulati
