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4-Hydroxy-2-(2-pyridinyl)-5-pyrimidinecarboxylic acid, also known as ASC-73513, is a chemical compound with the formula C11H8N2O3. It belongs to the family of pyrimidines and pyrimidine derivatives, which are aromatic compounds containing one or more pyrimidine rings. These rings consist of six members with two nitrogen atoms and four carbon atoms. The specific structure of 4-hydroxy-2-(2-pyridinyl)-5-pyrimidinecarboxylic acid includes a hydroxy group (-OH), a pyridinyl group (a nitrogen-containing ring), and a carboxylic acid group (-COOH). Although its precise uses are not widely documented, it may be used in chemical research or have potential applications in medicinal chemistry due to its pyrimidine backbone.

56406-45-2

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56406-45-2 Usage

Uses

Used in Chemical Research:
4-hydroxy-2-(2-pyridinyl)-5-pyrimidinecarboxylic acid is used as a research compound for studying its chemical properties and potential interactions with other molecules. Its unique structure with a hydroxy group, a pyridinyl group, and a carboxylic acid group makes it an interesting candidate for various chemical reactions and analyses.
Used in Medicinal Chemistry:
4-hydroxy-2-(2-pyridinyl)-5-pyrimidinecarboxylic acid is used as a potential pharmaceutical compound for the development of new drugs. Its pyrimidine backbone and functional groups may offer opportunities for the design of novel therapeutic agents, particularly in the areas of cancer treatment or other diseases where pyrimidine-based compounds have shown promise. Further research is needed to explore its potential in this field and to understand its mechanism of action.

Check Digit Verification of cas no

The CAS Registry Mumber 56406-45-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,6,4,0 and 6 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 56406-45:
(7*5)+(6*6)+(5*4)+(4*0)+(3*6)+(2*4)+(1*5)=122
122 % 10 = 2
So 56406-45-2 is a valid CAS Registry Number.

56406-45-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-oxo-2-pyridin-2-yl-1H-pyrimidine-5-carboxylic acid

1.2 Other means of identification

Product number -
Other names hydroxypyridinylpyrimidinecarboxylicacid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:56406-45-2 SDS

56406-45-2Relevant academic research and scientific papers

Discovery of N-[Bis(4-methoxyphenyl)methyl]-4-hydroxy-2-(pyridazin-3-yl)pyrimidine-5-carboxamide (MK-8617), an Orally Active Pan-Inhibitor of Hypoxia-Inducible Factor Prolyl Hydroxylase 1-3 (HIF PHD1-3) for the Treatment of Anemia

Debenham, John S.,Madsen-Duggan, Christina,Clements, Matthew J.,Walsh, Thomas F.,Kuethe, Jeffrey T.,Reibarkh, Mikhail,Salowe, Scott P.,Sonatore, Lisa M.,Hajdu, Richard,Milligan, James A.,Visco, Denise M.,Zhou, Dan,Lingham, Russell B.,Stickens, Dominique,Demartino, Julie A.,Tong, Xinchun,Wolff, Michael,Pang, Jianmei,Miller, Randy R.,Sherer, Edward C.,Hale, Jeffrey J.

, p. 11039 - 11049 (2016/12/30)

The discovery of novel 4-hydroxy-2-(heterocyclic)pyrimidine-5-carboxamide inhibitors of hypoxia-inducible factor (HIF) prolyl hydroxylases (PHD) is described. These are potent, selective, orally bioavailable across several species, and active in stimulati

SUBSTITUTED PYRIMIDINES

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Page/Page column 33, (2013/04/10)

Disclosed are substituted pyrimidines useful as HIF prolyl hydroxylase inhibitors to treat anemia and like conditions.

SUBSTITUTED PYRIMIDINES

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Page/Page column 32; 33, (2013/04/10)

The present invention relates to substituted pyrimidines useful as HIF prolyl hydroxylase inhibitors to treat anemia and like conditions.

SUBSTITUTED PYRIMIDINES

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Page/Page column 53, (2011/11/06)

The present invention relates to substituted pyrimidines useful as HIF prolyl hydroxylase inhibitors to treat anemia and like conditions.

SUBSTITUTED PYRIMIDINES

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Page/Page column 52, (2011/11/06)

The present invention relates to substituted pyrimidines useful as HIF prolyl hydroxylase inhibitors to treat anemia and like conditions.

Substituted 4-Hydroxypyrimidine-5-Carboxamides

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Page/Page column 27, (2009/10/01)

The present invention relates to substituted 4-hydroxypyrimidine-5-carboxamides useful as HIF prolyl hydroxylase inhibitors to treat anemia and like conditions.

Bis(4-[4'-hydroxy-5'-carboxy-2'-pyrimidinyl]phenoxy)alkanes

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, (2008/06/13)

5-Carboxypyrimidine derivatives and their pharmaceutically acceptable basic salts, and their use as antiallergy agents.

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