60061-68-9 Usage
Uses
Used in Organic Synthesis:
4-Bromo-3-methyl-5-(trifluoromethyl)-1H-pyrazole is utilized as a key intermediate in organic synthesis for the preparation of a variety of chemical compounds. Its reactivity and structural features make it suitable for the formation of new chemical entities with potential applications in various fields.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 4-Bromo-3-methyl-5-(trifluoromethyl)-1H-pyrazole is employed as a building block for the synthesis of biologically active molecules. Its unique combination of functional groups allows for the development of compounds with specific therapeutic properties, contributing to the advancement of new medications.
Used in Medicinal Chemistry:
4-Bromo-3-methyl-5-(trifluoromethyl)-1H-pyrazole is used as a versatile tool in medicinal chemistry. 4-Bromo-3-methyl-5-(trifluoromethyl)-1h-pyrazole's ability to interact with a wide range of reagents and functional groups facilitates the design and synthesis of novel drug candidates with improved pharmacological profiles.
Used in Novel Drug Discovery:
The presence of the trifluoromethyl group in 4-Bromo-3-methyl-5-(trifluoromethyl)-1H-pyrazole endows the compound with distinct physical and chemical properties. This feature is harnessed in drug discovery processes to create new pharmaceutical agents with potentially enhanced efficacy, selectivity, and pharmacokinetic properties.
Check Digit Verification of cas no
The CAS Registry Mumber 60061-68-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,0,6 and 1 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 60061-68:
(7*6)+(6*0)+(5*0)+(4*6)+(3*1)+(2*6)+(1*8)=89
89 % 10 = 9
So 60061-68-9 is a valid CAS Registry Number.
InChI:InChI=1/C5H4BrF3N2/c1-2-3(6)4(11-10-2)5(7,8)9/h1H3,(H,10,11)
60061-68-9Relevant academic research and scientific papers
2-[4-(PYRAZOL-4-YLALKYL)PIPERAZIN-1-YL]-3-PHENYL PYRAZINES AND PYRIDINES AND 3-[4-(PYRAZOL-4-YLALKYL)PIPERAZIN-1-YL]-2-PHENYL PYRIDINES AS 5-HT7 RECEPTOR ANTAGONISTS
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Page/Page column 51, (2009/01/20)
The present invention provides selective 5-HT7 receptor antagonist compounds of Formula I and their use in the treatment of migraine, persistent pain, and anxiety: where A and B are each independently C(H)= or N=, provided that at least one of A and B is -N=, n is 1-3, m is 0-3, and R14 are as defined herein.
Synthesis of novel 1,4,5-trisubstituted 3-trifluoromethylpyrazoles via microwave-assisted Stille coupling reactions
Jeon, Sung Lan,Choi, Ji Hoon,Kim, Bum Tae,Jeong, In Howa
, p. 1191 - 1197 (2008/02/10)
1,5-Disubstituted 3-trifluoromethylpyrazoles were reacted with N-bromosuccinimide in DMF at room temperature or 70-80 °C for 1-2 h to afford the corresponding 4-bromo-substituted pyrazoles 2 in 95-99% yields. The microwave-assisted Stille coupling reactio
