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60078-16-2

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60078-16-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 60078-16-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,0,7 and 8 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 60078-16:
(7*6)+(6*0)+(5*0)+(4*7)+(3*8)+(2*1)+(1*6)=102
102 % 10 = 2
So 60078-16-2 is a valid CAS Registry Number.

60078-16-2Relevant articles and documents

Bioorthogonal Click and Release Reaction of Iminosydnones with Cycloalkynes

Bernard, Sabrina,Audisio, Davide,Riomet, Margaux,Bregant, Sarah,Sallustrau, Antoine,Plougastel, Lucie,Decuypere, Elodie,Gabillet, Sandra,Kumar, Ramar Arun,Elyian, Jijy,Trinh, Minh Nguyet,Koniev, Oleksandr,Wagner, Alain,Kolodych, Sergii,Taran, Frédéric

, p. 15612 - 15616 (2017/12/02)

We report the discovery of a new bioorthogonal click-and-release reaction involving iminosydnones and strained alkynes. This transformation leads to two products resulting from the ligation and fragmentation of iminosydnones under physiological conditions. Optimized iminosydnones were successfully used to design innovative cleavable linkers for protein modification, thus opening up new areas in the fields of drug release and target-fishing applications. This click-and-release technology offers the possibility of exchanging tags on proteins for functionalized cyclooctynes under mild and bioorthogonal conditions.

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