60081-99-4

Basic information

• Product Name: Benzonitrile, 4-(dimethylamino)-3-methyl-
• Synonyms: Benzonitrile,4-(dimethylamino)-3-methyl;4-dimethylamino-3-methyl-benzonitrile;2-methyl-4-cyano-N,N-dimethylaniline
• CAS NO: 60081-99-4
• Molecular Formula: C10H12N2
• Molecular Weight: 160.219
• Mol File: 60081-99-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 328.8±22.0 °C(Predicted)
• Density: 1.03±0.1 g/cm3(Predicted)
• CAS DataBase Reference: Benzonitrile, 4-(dimethylamino)-3-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzonitrile, 4-(dimethylamino)-3-methyl-(60081-99-4)
• EPA Substance Registry System: Benzonitrile, 4-(dimethylamino)-3-methyl-(60081-99-4)

Safety Data

• Hazardous Substances Data: 60081-99-4(Hazardous Substances Data)

Upstream product

• 124-40-3 dimethyl amine 
• 185147-08-4 4-fluoro-3-methylbenzonitrile 

Downstream Products

• 1207840-79-6 5-chloro-7-(4-dimethylamino-3-methylphenyl)-[1,6]naphthyridine 
• 1207840-60-5 5-methoxy-7-(4-dimethylamino-3-methylphenyl)-[1,6]naphthyridine 
• 1207840-64-9 5-(cyclopropylamino)-7-(4-dimethylamino-3-methylphenyl)-[1,6]naphthyridine 
• 1207840-45-6 trans-5-(4-hydroxycyclohexyl)-7-(4-dimethylamino-3-methylphenyl)-[1,6]naphthyridine 
• 1207840-44-5 cis-5-(4-hydroxycyclohexyloxy)-7-(4-dimethylamino-3-methylphenyl)-[1,6]naphthyridine 
• 1207840-46-7 5-(3-(aminomethyl)pyrrolidin-1-yl)-7-(4-dimethylamino-3-methylphenyl)-[1,6]naphthyridine 
• 1207840-47-8 5-(pyrrolidin-3-yl-methoxy)-7-(4-dimethylamino-3-methylphenyl)-[1,6]naphthyridine 
• 1207840-49-0 5-(2-(4-pyrazolyl)ethylamino)-7-(4-dimethylamino-3-methylphenyl)-[1,6]naphthyridine 
• 1207840-80-9 7-(4-dimethylamino-3-methylphenyl)-[1,6]naphthyridin-5-yl trifluoromethanesulphonate 
• 1207840-55-8 5-(4-(2-hydroxyethyl)pyrazol-1-yl)-7-(4-(dimethylamino)-3-methylphenyl)-[1,6]naphthyridine 
• 1207840-81-0 tert-butyl 2-{1-[7-[4-(dimethylamino)-3-methylphenyl]-[1,6]naphthyridin-5-yl]-1H-pyrazol-4-yl}ethylcarbonate 
• 1207840-66-1 5-((pyrrolidin-2-on-4-yl)methylhydroxy)-7-(4-(dimethylamino)-3-methylphenyl)-[1,6]naphthyridine 
• 1207840-78-5 7-(4-dimethylamino-3-methylphenyl)-[1,6]naphthyridin-5-ol 

Relevant articles and documents

4-DIMETHYLAMINO-PHENYL-SUBSTITUTED NAPHTHYRIDINES, AND USE THEREOF AS MEDICAMENTS

The invention relates to novel substituted naphthyridines of formula 1 as well as pharmacologically acceptable salts, diastereomers, enantiomers, racemates, hydrates, or solvates thereof. In formula 1, R1 can represent a group A selected from among the group comprising —O—R3, —NR3 R4, —CR3R4R5, -(ethyne)-R3, —S—R3, —SO—R3, and SO2—R3, or R1 represents a group B selected from among the group comprising: —C6-10-aryl;—a five-membered to ten-membered, monocyclic or bicyclic heteroaryl containing 1 to 3 heteroatoms independently selected from among the group comprising N, O, and S, wherein said heteroaryl is linked to the structure according to formula 1 via a C atom or an N atom;—a three-membered to ten-membered, monocyclic or bicyclic, saturated or partially saturated heterocycle containing 1 to 3 heteroatoms independently selected from among the group comprising N, O, and S, wherein said heterocycle is linked to the structure according to formula 1 via a C atom or an N atom; and—a 5-membered to 11-membered spiro group which can optionally contain 1, 2, or 3 heteroatoms independently selected from among the group comprising N, O, and S, wherein said spiro group is linked to the structure according to formula 1 via a C atom or an N atom, wherein said group B can be optionally substituted as described in claims 1, and R3,R4,R5,R6, and m can have the meanings indicated in claim 1. The invention also relates to pharmaceutical compositions containing said compounds.