60083-15-0

Upstream product

• 141-97-9 ethyl acetoacetate 
• 297766-64-4 1,3-Diphenyltriazen 
• 100-34-5 benzene diazonium chloride 
• 62-53-3 aniline 

Downstream Products

• 132934-83-9 5-Acetyl-3-phenyl-2-thioxo-2,3-dihydro-[1,3,4]thiadiazin-6-one 
• 132934-80-6 C₁₃H₁₃N₂O₃S₂^(1-)*Na⁽¹⁺⁾ 
• 13572-24-2 3-methyl-4-(2-phenylhydrazono)-1H-pyrazol-5(4H)-one 
• 6017-59-0 3-methyl-4-phenylhydrazonoisoxazol-5-one 
• 125040-83-7 C₁₉H₁₃N₃O₂ 
• 132934-86-2 5-Acetyl-3-phenyl-2-[(Z)-phenylimino]-2,3-dihydro-[1,3,4]thiadiazin-6-one 
• 132935-10-5 3-methyl-5-oxo-4-phenylhydrazono-4,5-dihydro-pyrazole-1-carboxylic acid amide 
• 89516-24-5 ethyl 5-cyano-4-methyl-6-oxo-1-phenyl-1,6-dihydropyridazine-3-carboxylate 
• 26178-92-7 1-thiocarboxamido-3-methyl-4-(phenylhydrazono)-2-pyrazolin-5-one 
• 125058-25-5 5-Cyano-4-((E)-2-furan-2-yl-vinyl)-6-oxo-1-phenyl-1,6-dihydro-pyridazine-3-carboxylic acid ethyl ester 
• 125040-86-0 5-Cyano-4-[(E)-2-(4-methoxy-phenyl)-vinyl]-6-oxo-1-phenyl-1,6-dihydro-pyridazine-3-carboxylic acid ethyl ester 
• 125040-97-3 5-Cyano-6-oxo-1-phenyl-4-(2-piperidin-1-yl-ethyl)-1,6-dihydro-pyridazine-3-carboxylic acid ethyl ester 
• 125040-92-8 ethyl-5-amino-6-cyano-7-(2-furyl)-4-oxo-3-phenyl-3,4-dihydro-1-phthalazinecarboxylate 
• 125040-91-7 5-Amino-6-cyano-7-(4-methoxy-phenyl)-4-oxo-3-phenyl-3,4-dihydro-phthalazine-1-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

Sydnone derivatives. Part VII: Synthesis of some novel thiazoles and their pharmacological properties

The synthesis of some 4-(arylsydnonyl)-2- (4-arylhydrazono-3-methyl-5-oxo-2-pyrazolin-1-yl)-thiazoles by reacting 1-thiocarboxamido-3-methyl-4-(arylhydrazono)-2-pyrazolin-5-ones with different 4-bromoacetyl-3-arylsydnones is described. A few compounds from this series were screened for their anti-inflammatory, analgesic, and CNS depressant activities. Among the tested compounds 6s, 6d, 6n, and 6u showed significant anti-inflammatory activity comparable with that of standard drug Ibuprofen. Compounds containing chlorine and carboxylic substituents are more active. 6f, 6r, and 6u showed marked analgesic activity and most of the compounds tested showed promising CNS depressant activity comparable with that of standard drug pentobarbitone.

Dihydropyridine structure contained 7-nitrogenous indoles compound and application thereof

The invention discloses a dihydropyridine structure contained 7-nitrogenous indoles compound and geometrical isomer, pharmacologically acceptable salt, hydrate, solvate or prodrug and preparation method thereof. The dihydropyridine structure contained 7-nitrogenous indoles compound and the pharmacologically acceptable salt, hydrate or solvate serve as activities and are mixed and prepared into the compound with a pharmacologically acceptable carrier or a polybutene, and the clinically acceptable dosage form is prepared. The dihydropyridine structure contained 7-nitrogenous indoles compound is applied to preparation of disease drugs in treatment and/or prevention of hyperplastic disease, cancer and lung cancer, liver cancer, stomach cancer, colon cancer and breast cancer.

A microwave assisted diazo coupling reaction: The synthesis of alkylazines and thienopyridazines

Heating diazoaminobenzene with active methylene compounds 1-3 in microwave oven in acetic acid, in the presence of hydrochloric acid, afforded the corresponding arylhydrazones 5-7. These reaction products were condensed with ethyl cyanoacetate in a domestic microwave oven after 1-2 minutes heating to yield the pyridazinones 8-12. Compounds 8c and 12 reacted with sulfur in basic DMF solution, in microwave oven using MORE technology to yield the thienopyridazinone 14 and 16 respectively. While 17 was produced when 8b was treated like wise with sulfur and DMF in the presence of piperidine. Compounds 16 coupled with aromatic diazonium salts to yield arylazo derivatives 21a-c. Copyright Taylor & Francis Group, LLC.

Morphinoid derivatives as delta-opioid agonists and antagonists

Compounds of formula (I) in which R1 is hydrogen or alkyl; R2 is hydrogen or one or more alkyl groups; R3 is R1 or R1X—; wherein R1 is hydrogen or optionally substituted alkyl, aryl, arylal

Synthesis, characterization and antimicrobial studies of some novel 3- arylazo-7-hydroxy-4-methylcoumarins

A series of 3-arylazo-7-hydroxy-4-methylcoumarins have been synthesized in excellent yields (80-90%) and their structures established on the basis of IR, 1H NMR, mass spectral data and elemental analyses. Their purity has been ascertained by ch

1,2,3-Triazole N-Oxides. II. Synthesis of Substituted 4(5)-Ethoxycarbonyl-1,2,3-triazole N-Oxides

Oxidative cyclization of ethyl 2-hydrazono-3-hydroxyimino- and 3-hydrazono-2-hydroxyiminobutanoates in the presence of γ-MnO2 yields isomeric 4(5)-methyl-2-phenyl-5(4)-ethoxycarbonyl-1,2,3-triazole 1-oxides. Alkaline hydrolysis and ammonolysis

Cyclopentapyrazole and tetrahydroindazole compounds and their use as anti-inflammatory and anti-allergic agents

The present invention provides novel compositions of matter and their therapeutic applications. More particularly, the present invention consists of novel cyclopentapyrazole and tetrahydroindazole compounds of formula XXX and their use as antiallergy agents, antiinflammatory agents or intermediates. STR1