60093-15-4

Usage

Uses

Used in Pharmaceutical Industry:
3-AMINO-5-PHENYLAMINO-1,2,4-THIADIAZOLE is used as a building block for the development of new therapeutic agents due to its potential applications in medicinal chemistry.
Used in Agrochemical Industry:
3-AMINO-5-PHENYLAMINO-1,2,4-THIADIAZOLE is used in the synthesis of agrochemicals, contributing to the development of new products for agricultural applications.
Used in Drug Discovery Research:
3-AMINO-5-PHENYLAMINO-1,2,4-THIADIAZOLE is used as a subject of interest in drug discovery research due to its demonstrated potential antitumor and antiviral activities.

Upstream product

• 15989-47-6 1-phenyl-3-guanylthiourea 
• 103-72-0 phenyl isothiocyanate 

Downstream Products

• 97283-87-9 N-(2-acetyl-3-acetylimino-2,3-dihydro-[1,2,4]thiadiazol-5-yl)-N-phenyl-acetamide 
• 54356-29-5 N-(5-anilino-[1,2,4]thiadiazol-3-yl)-benzamide 
• 104424-07-9 N-(2-benzoyl-3-benzoylimino-2,3-dihydro-[1,2,4]thiadiazol-5-yl)-N-phenyl-benzamide 
• 93734-57-7 N-(5-anilino-[1,2,4]thiadiazol-3-yl)-toluene-4-sulfonamide 
• 107101-21-3 N-phenyl-N-[2-(toluene-sulfonyl)-3-(toluene-4-sulfonylimino)-2,3-dihydro-[1,2,4]thiadiazol-5-yl]-toluene-4-sulfonamide 
• 93647-51-9 N-(5-anilino-[1,2,4]thiadiazol-3-yl)-3-nitro-benzenesulfonamide 
• 91688-32-3 N-(3-acetylamino-[1,2,4]thiadiazol-5-yl)-N-phenyl-acetamide 
• 2254-85-5 (3-chloro-[1,2,4]thiadiazol-5-yl)-phenyl-amine 
• 97149-64-9 5-anilino-3-(N'-benzoylureido)-1,2,4-thiadiazole 

Relevant academic research and scientific papers

Co-Catalyzed Intramolecular S-N Bond Formation in Water for 1,2-Benzisothiazol-3(2H)-ones and 1,2,4-Thiadiazoles Synthesis

An efficient and versatile Co-catalyzed intramolecular S-N bond formation in water to synthesize 1,2-benzisothiazol-3(2H)-one and 1,2,4-thiadiazoles derivatives in good to excellent yields was developed. The transformation showed great tolerance with a broad range of substituents. The mother liquor was able to be recycled 6 times with minor loss in product yield.

Synthesis of 5-Amino and 3,5-Diamino Substituted 1,2,4-Thiadiazoles by I2-Mediated Oxidative N-S Bond Formation

An oxidative N-S bond formation reaction has been established for 1,2,4-thiadiazole synthesis employing molecular iodine as the sole oxidant. The features of the present reaction include no use of transition metals, mild reaction conditions, simple operat

A facile synthesis of novel nitrogen-sulphur heterocycles containing the amidino moiety and their antimicrobial activity - Part I

The interaction of amidinothiocarbamide 1 and 4-bromo-1,3-substituted-pyrazol-5-ones 1 afford 2-guanidino-4, 6-substituted-pyrazolo [5,4-d]thiazoles 5 on reaction with aldehydes yield the corresponding schiff's bases bases 6. An alternate unambiguous one

Oxidative heterocyclization using diethyl azodicarboxylate

The reactions of amidinothioureas, imidoylthioureas, thioacylamidines, O-methyl-1-aryl-2-thioisobiurets, and 1-aryl-isodithiobiurets with diethyl azodicarboxylate (DEAD, diethyl diazenedicarboxylate) gave the corresponding thiadiazoles by the oxidative cy