60111-76-4 Usage
Uses
Used in Pharmaceutical Industry:
BOC-D-LEU-OSU is used as a synthetic building block for the development of peptide-based drugs. Its incorporation into peptide structures allows for the creation of novel therapeutic agents with enhanced properties, such as improved stability, bioavailability, and target specificity.
Used in Peptide Synthesis:
BOC-D-LEU-OSU is used as a key component in the synthesis of peptide gastrin antagonists. These antagonists are designed to block the action of gastrin, a hormone that stimulates the secretion of gastric acid. By inhibiting gastrin's effects, these peptide antagonists can be used to treat conditions such as ulcers and other gastrointestinal disorders.
Used in Antibiotic Development:
BOC-D-LEU-OSU is also utilized in the synthesis of analogs of the peptide antibiotic gramicidin S. Gramicidin S is a potent antibiotic that acts by disrupting the cell membrane of bacteria, leading to cell death. The development of analogs using BOC-D-LEU-OSU can potentially enhance the efficacy of gramicidin S and expand its range of applications against various bacterial pathogens.
Check Digit Verification of cas no
The CAS Registry Mumber 60111-76-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,1,1 and 1 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 60111-76:
(7*6)+(6*0)+(5*1)+(4*1)+(3*1)+(2*7)+(1*6)=74
74 % 10 = 4
So 60111-76-4 is a valid CAS Registry Number.
60111-76-4Relevant academic research and scientific papers
LE CHLOROFORMIATE D'ISOPROPENYLE (IPCF) EN CHIMIE DES AMINO-ACIDES ET DES PEPTIDES - III SYNTHESE D'ESTERS ACTIFS D'AMINO ACIDES N-PROTEGES
Jaouadi, M.,Selve, C.,Dormoy, J. R.,Castro, B.,Martinez, J.
, p. 1721 - 1722 (2007/10/02)
Isopropenyl chloroformate (IPCF) was used for preparation of mixed carbonates (Aryl and isopropenyl) which are very suitable reagents for active ester synthesis of amino acid derivatives (Boc derivatives in particular).
