60112-48-3Relevant academic research and scientific papers
A Piperine-Based Scaffold as a Novel Starting Point to Develop Inhibitors against the Potent Molecular Target OfChtI
Deng, Ming-Fei,Duan, Hong-Xia,Han, Qing,Li, Hui-Lin,Li, Xiang,Wang, Jin-E,Wu, Nan,Yang, Qing,Zhang, Jing-Yu,Zhu, Kai
, (2021/07/26)
The insect chitinase OfChtI from the agricultural pest Ostrinia furnacalis (Asian corn borer) is a promising target for green insecticide design. OfChtI is a critical chitinolytic enzyme for the cuticular chitin degradation at the stage of molting. In thi
Compound with piperine skeleton structure as well as preparation and application thereof
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Paragraph 0034; 0037-0038, (2020/07/02)
The invention discloses a compound with a piperine skeleton structure as well as preparation and application of the compound, wherein the structural formulas of the compound are shown as a formula I-1and a formula I-2; in the formulas, R1 is hydrogen, halogen, nitryl or cyano, or substituted or unsubstituted hydroxyl, amino, carboxyl, ester group, hydrosulfenyl, acylamino, ureido, C1-C5 straight-chain or branched-chain alkyl and C1-C5 alkoxy; R2 is hydrogen, halogen, nitro or cyano, or substituted or unsubstituted hydroxyl, amino, carboxyl, ester group, hydrosulfenyl, acylamino, ureido, phenyl, aryl and aromatic heterocyclic group, or substituted or unsubstituted C1-C5 straight-chain or branched-chain alkyl, or substituted or unsubstituted C1-C5 alkoxy, or substituted or unsubstituted C6-C30 aryl, fused ring and fused heterocyclic ring. As a chitinase inhibitor, the compound provided by the invention has the advantages of high activity, good broad spectrum and easiness in synthesis, and shows excellent insecticidal ability and insecticidal spectrum.
A facile synthesis of γ-butenolides via cyclization of 3-alkenoic acids with dimethyl sulfoxide and oxalyl bromide
Ding, Rui,Liu, Yongguo,Liu, Lei,Li, Huimin,Tao, Sichen,Sun, Baoguo,Tian, Hongyu
supporting information, p. 3001 - 3007 (2019/08/26)
The combination of dimethyl sulfoxide and oxalyl bromide was used to accomplish the cyclization of 3-alkenoic acids with the aid of a base to afford γ-butenolides, in which bromodimethylsulfonium salt generated in situ was proposed to serve as a Br+ source.
Facile oxidation of aldehydes to acids and esters with Oxone
Travis, Benjamin R.,Sivakumar, Meenakshi,Hollist, G. Olatunji,Borhan, Babak
, p. 1031 - 1034 (2007/10/03)
(Matrix presented) A highly efficient, mild, and simple protocol is presented for the oxidation of aldehydes to carboxylic acids utilizing Oxone as the sole oxidant. Direct conversion of aldehydes in alcoholic solvents to their corresponding ester products is also reported. These reactions may prove to be valuable alternatives to traditional metal-mediated oxidations.
Catalytic osmium-assisted oxidative cleavage of olefins
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, (2008/06/13)
An osmium-assisted process for the oxidative cleavage of oxidizable organic compounds such as unsaturated organic compounds, including alkenes and olefins into aldehydes, carboxylic acids, esters, or ketones. The process uses a metal catalyst comprising osmium and a peroxy compound selected from the group consisting of peroxymonosulfuric acid and salts thereof to oxidatively cleave the oxidizable organic compound. In particular, the process enables aldehydes, carboxylic acids, esters, or ketones to be selectively produced from the corresponding mono-, 1,1-di-, 1,2-di-, tri-, or tetra-substituted olefins in a reaction that produces the result of ozonolysis but with fewer problems. The present invention further provides a process for oxidizing an aldehyde alone or with the osmium in an interactive solvent to produce an ester or carboxylic acid.
MELDRUM'S ACID - A REAGENT FOR THE SYNTHESIS OF UNSATURATED γ-LACTONES AND β-ACYLACRYLIC ACIDS
Zav'yalov, S. I.,Zavozin, A. G.,Kravchenko, N. E.
, p. 1090 - 1092 (2007/10/02)
The thermal cyclization of 2,2-dimethyl-5-(2-aryl-2-oxoethyl)-1,3-dioxan-4,6-diones forms 5-aryl-β,γ-butenolides.Regioselective chlorination of 2,2-dimethyl-5--1,3-dioxane-4,6-diones by SO2Cl2 gives the 5-chloro derivatives, thes
Some Observations Concerning the Lactonization of 3-Aroylpropionic Acids
Tsolomitis, A.,Sandris, C.
, p. 1545 - 1548 (2007/10/02)
The ease of lactonization og the γ-keto acids ArCOCH2CH2COOH is shown to depend on the nature of the aryl group: the presence of electron-releasing substituents on the aryl group results in a more rapid reaction as compared to the presence of electron-wit
