60129-60-4

Basic information

• Product Name: glucosilsteviol
• Synonyms: glucosilsteviol;13-(β-D-Glucopyranosyloxy)kaur-16-en-18-oic acid;Steviolmonoside;Steviol-monoside
• CAS NO: 60129-60-4
• Molecular Formula: C₂₆H₄₀O₈
• Molecular Weight: 480.594
• Mol File: 60129-60-4.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 666°C at 760 mmHg
• Flash Point: 220.6°C
• Appearance: /
• Density: 1.34g/cm³
• Vapor Pressure: 1.4E-20mmHg at 25°C
• Refractive Index: 1.604
• CAS DataBase Reference: glucosilsteviol(CAS DataBase Reference)
• NIST Chemistry Reference: glucosilsteviol(60129-60-4)
• EPA Substance Registry System: glucosilsteviol(60129-60-4)

Safety Data

• Hazardous Substances Data: 60129-60-4(Hazardous Substances Data)

Usage

General Description

Glucosilsteviol is a chemical compound derived from the leaves of the Stevia rebaudiana plant. It is a natural sweetener that is much sweeter than sugar and has gained popularity as a sugar substitute in food and beverage products. Glucosilsteviol is composed of glucose molecules linked to the steviol glycoside molecule, which is responsible for its intense sweetness. It is often used as an ingredient in low-calorie and sugar-free products, providing a sweet taste without the calories or adverse effects on blood sugar levels. Studies have shown that glucosilsteviol is safe for consumption and does not have the same negative health effects as sugar, making it a popular option for those looking to reduce their sugar intake.

InChI:InChI=1/C26H40O8/c1-14-11-25-9-5-16-23(2,7-4-8-24(16,3)22(31)32)17(25)6-10-26(14,13-25)34-21-20(30)19(29)18(28)15(12-27)33-21/h15-21,27-30H,1,4-13H2,2-3H3,(H,31,32)

Upstream product

• 29584-19-8 steviol 
• 133-89-1 UDP-glucose 
• 64849-39-4 13-O-β-D-glucopyranosyl-19-O-β-D-glucopyranosylsteviol 
• 134150-21-3 13-O-β-D-glucosyl-19-O-β-maltopentosylsteviol 
• 134150-16-6 13-O-β-D-glucosyl-19-O-β-maltotetrosylsteviol 
• 57817-89-7 stevioside 
• 64849-39-4 steviol 13-O-β-glucopyranoside 19-β-glucopyranosyl ester 

Downstream Products

• 64849-39-4 13-O-β-D-glucopyranosyl-19-O-β-D-glucopyranosylsteviol 
• 104873-42-9 C₃₂H₅₀O₁₃ 
• 64849-39-4 steviol 13-O-β-glucopyranoside 19-β-glucopyranosyl ester 
• 93973-87-6 C₃₈H₆₀O₁₈ 
• 93973-88-7 C₄₄H₇₀O₂₃ 
• 120602-96-2 C₅₆H₉₀O₃₃ 
• 120602-95-1 C₅₀H₈₀O₂₈ 

Relevant articles and documents

Further study on the 1,4-alpha-transglucosylation of rubusoside, a sweet steviol-bisglucoside from Rubus suavissimus.

Rubusoside (the beta-D-glucosyl ester of 13-O-beta-D-glucosyl-steviol), which is the major sweet principle of leaves of Rubus suavissimus S. Lee, was subjected to 1,4-alpha-transglucosylation by the cyclodextringlucanotransferase-starch system (the CGTase system). The tri- and tetra-glucosylated products were isolated together with the mono- and di-glucosylated products, which had already been isolated. A prominent increase in intensity of the sweetness was observed for the compounds which were di- and tri-glucosylated at the 13-O-glucosyl moiety. This result further substantiated the structure-sweetness relationship for 1,4-alpha-glucosylated compounds of steviol-glycosides reported previously. For protection of the 19-COO-glucosyl moiety against glucosylation by the CGTase system, the 4-hydroxyl group of the 19-COO-glucosyl moiety was beta-galactosylated by the beta-galactosidase-lactose system. This galactosylated compound was subjected to a regio-selective glucosylation of the 13-O-glucosyl moiety by the CGTase system, which was followed by enzymic elimination of the galactosyl group to furnish an exclusive preparation of the improved sweeteners just mentioned.

Glucosyltransferase Capable of Catalyzing the Last Step in Neoandrographolide Biosynthesis

ApUGT, a diterpene glycosyltransferase from Andrographis paniculata, could transfer a glucose to the C-19 hydroxyl moiety of andrograpanin to form neoandrographolide. This glycosyltransferase has a broad substrate scope, and it can glycosylate 26 natural and unnatural compounds of different structural types. This study provides a basis for exploring the glycosylation mechanism of ent-labdane-type diterpenes and plays an important role in diversifying the structures used in drug discovery.

PRODUCTION OF STEVIOL GLYCOSIDES IN RECOMBINANT HOSTS

The invention relates to recombinant microorganisms and methods for producing steviol glycosides, glycosylated ent-kaurenol, and glycosylated ent-kaurenoic acid.