60148-77-8

Upstream product

• 132034-50-5 (Z)-2,6-dimethylphenyl-1'-methyl-2'-methoxyethyl-imine 
• 87-62-7 2,6-dimethylaniline 
• 85385-06-4 2,6-dimethylphenyl-1'-methyl-2'-methoxyethyl-imine 

Downstream Products

• 68544-96-7 N-(1'-methyl-2'-methoxyethyl)-N-ethoxyacetyl-2,6-dimethylaniline 
• 68545-13-1 N-(2,6-Dimethyl-phenyl)-3-methoxy-N-(2-methoxy-1-methyl-ethyl)-propionamide 
• 68545-06-2 N-(2,6-Dimethyl-phenyl)-N-(2-methoxy-1-methyl-ethyl)-2-propoxy-acetamide 
• 68545-19-7 N-(2,6-Dimethyl-phenyl)-3-ethoxy-N-(2-methoxy-1-methyl-ethyl)-propionamide 
• 126404-31-7 3-[(2,6-Dimethyl-phenyl)-(2-methoxy-1-methyl-ethyl)-carbamoyl]-but-3-enoic acid methyl ester 
• 1331827-03-2 Ti(N-(1-methoxypropan-2-yl)-2,6-dimethylaniline(-1H))(dimethylamido)3 
• 1331827-02-1 Zr(N-(1-methoxypropan-2-yl)-2,6-dimethylaniline(-1H))(dimethylamido)3 

Relevant academic research and scientific papers

Intermolecular hydroamination of oxygen-substituted allenes. New routes for the synthesis of N,O-chelated zirconium and titanium amido complexes

Intermolecular hydroamination of heteroatom-substituted allenes with a bulky arylamine was carried out using a bis(amidate) bis(amido) titanium(iv) complex (1) as a precatalyst. The reaction of 2,6-dimethylaniline with oxygen-substituted allene 2c or 2d i

Process for the preparation of secondary amines

N,N-disubstituted amines in which the amino nitrogen atom is bound to the carbon atom of an aromatic ring disubstituted in the positions ortho to the carbon atom, are prepared by allowing a primary amine and a compound in which an ortho, ortho-disubstituted aromatic compound carrying a nucleofuge substituent, to react in a basic environment in the presence of a catalytic palladium(0) complex and a ligand, the ratio of palladium complex to ligand being greater than at least 1:1. A typical embodiment involves the reaction of 2-methyl-6-ethylphenyl-trifluoromethylsulfonate and (S)-1-methoxy-2-aminopropane in the presence of bis(dibenzylideneacetone)palladium, tri-tert.-butylphosphine, and sodium tert.-butoxide to yield (S)-N-(1-methoxyprop-2-yl)-2-methyl-6-ethylphenylamine.

The asymmetric hydrogenation of imines using tridentate C2 diphosphine complexes of iridium(I) and rhodium(I)

We report the synthesis of [M(PNP)(diene)]+ complexes (M = Ir or Rh; diene = COD or NBD), where PNP represents a tridentate diphosphine ligand of C2 symmetry. These complexes are active catalysts for the hydrogenation of imines. Reduction of prochiral iminess in the presence of chiral ligands leads to the corresponding amines with 7 to 55% ee.

Ferrocenyl diphosphines as ligands for homogeneous catalysts

Compounds of formula I STR1 wherein R1 is C1 -C8 alkyl, phenyl or phenyl which is substituted by 1 to 3 C1 -C4 alkyl or C1 -C4 alkoxy groups; R2 and R3 are identical and are C1 -C12 alkyl, C5 -C12 cycloalkyl or C1 -C4 alkyl- or C1 -C4 alkoxy-substituted C5 -C12 cycloalkyl, or phenyl which is substituted by one to three identical or different members selected from the group consisting of C1 -C4 alkyl, C1 -C4 alkoxy, --SiR4 R5 R6, halogen, --SO3 M, --CO2 M, --PO3 M,--NR7 R8 and --[≈ NR7 R8 R9 ]X? ; or R2 and R3 are different and are C1 -C12 alkyl, C5 -C12 cycloalkyl, C1 -C4 alkyl- or C1 -C4 alkoxy-substituted C5 -C12 cycloalkyl, phenyl or phenyl which is substituted by one to three identical or different members selected from the group consisting of C1 -C4 alkyl, C1 -C4 alkoxy, --SiR4 R5 R6, halogen, --SO3 M, --CO2 M, --PO3 M2, --NR7 R8 and --[≈NR7 R8 R9 ]X? ; or the group --PR2 R3 is a radical of formula II STR2 and R4, R5 and R6 are each independently of one another C1 -C12 alkyl or phenyl, R7 and R8 are H, C1 -C2 alkyl, phenyl or R7 and R8, taken together, are tetramethylene, pentamethylene or 3-oxa-1,5-pentylene, R9 is H or C1 -C4 alkyl, M is H or an alkali metal, X? is the anion of a monobasic acid, and * is a stereogenic carbon atom, in the form of their racemates and diastereoisomers or mixtures of diastereoisomers. Rhodium and iridium complexes with these ligands are suitable for use as homogeneous enantioselective catalysts for the hydrogenation of prochiral compounds containing carbon double bonds or carbon/hetero atom double bonds.