601488-95-3Relevant academic research and scientific papers
Alkylation of phenylglycinol-derived oxazolopiperidone lactams. Enantioselective synthesis of β-substituted piperidines
Amat, Mercedes,Escolano, Carmen,Lozano, Oscar,Gomez-Esque, Arantxa,Griera, Rosa,Molins, Elies,Bosch, Joan
, p. 3804 - 3815 (2007/10/03)
The stereochemical outcome of the alkylation of a variety of phenylglycinol-derived oxazolopiperidone lactams is studied. The influence of the configuration of the C-8a stereocenter and the effect of the substituents at the C-8 and C-8a positions on the s
Enantioselective synthesis of cis- and trans-3,5-disubstituted piperidines. Synthesis of 20S- and 20R-dihydrocleavamine
Amat, Mercedes,Escolano, Carmen,Lozano, Oscar,Llor, Nuria,Bosch, Joan
, p. 3139 - 3142 (2007/10/03)
(Matrix presented) Diastereoselective alkylation at the carbonyl α-position of chiral nonracemic lactams 2 and 3, the former prepared by cyclocondensation of (R)-phenylglycinol with a racemic γ-substituted δ-oxoester in a process that involves a dynamic k
