601488-96-4

Upstream product

• 155796-96-6 (2'R,3S)-(-)-2-(3-methylpiperidin-1-yl)-2'-phenylethanol 
• 601488-95-3 (3R,6S,8S,8aR)-8-ethyl-6-methyl-5-oxo-3-phenyl-2,3,6,7,8,8a-hexahydro-5H-oxazolo[3,2-a]pyridine 
• 884315-12-2 (1'R,5S)-(-)-1-(2'-hydroxy-1'-phenylethyl)-5-methylpiperidin-2-one 
• 194149-76-3 (3R,8S,8aR)-8-ethyl-5-oxo-3-phenyl-2,3,6,7,8,8a-hexahydro-5H-oxazolo[3,2-a]pyridine 

Relevant academic research and scientific papers

Regioselective endocyclic oxidation of enantiopure 3-alkylpiperidines: Synthesis of (3S,5S)-(-)-3-ethyl-5-methylpiperidine

An efficient regioselective endocyclic oxidation of enantiopure 3-alkylpiperidines 1(a-c) with bromine in acetic acid to generate the corresponding 5-alkylpiperidin-2-ones 3(a-c) as main product is described. In addition, starting from 3a or 3b, the synth

Alkylation of phenylglycinol-derived oxazolopiperidone lactams. Enantioselective synthesis of β-substituted piperidines

The stereochemical outcome of the alkylation of a variety of phenylglycinol-derived oxazolopiperidone lactams is studied. The influence of the configuration of the C-8a stereocenter and the effect of the substituents at the C-8 and C-8a positions on the s

Enantioselective synthesis of cis- and trans-3,5-disubstituted piperidines. Synthesis of 20S- and 20R-dihydrocleavamine

(Matrix presented) Diastereoselective alkylation at the carbonyl α-position of chiral nonracemic lactams 2 and 3, the former prepared by cyclocondensation of (R)-phenylglycinol with a racemic γ-substituted δ-oxoester in a process that involves a dynamic k