60158-54-5Relevant academic research and scientific papers
Metal-catalyzed one-pot synthesis of tetrazines directly from aliphatic nitriles and hydrazine
Yang, Jun,Karver, Mark R.,Li, Weilong,Sahu, Swagat,Devaraj, Neal K.
, p. 5222 - 5225 (2012)
Paving the way: The lack of convenient synthetic methods is a significant roadblock to the broader use of 1,2,4,5-tetrazines in bioorthogonal chemistry and functional materials. Lewis acid metal catalysts-most notably divalent nickel and zinc salts-are described to catalyze the one-pot synthesis of 1,2,4,5-tetrazines directly from aliphatic nitriles (see scheme). Copyright
NOVEL TETRAZINES AND METHOD OF SYNTHESIZING THE SAME
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Paragraph 0283, (2013/10/22)
Provided herein, inter alia, are compositions and methods of synthesis and detection of tetrazines and diazonorcaradienes.
