60187-00-0

Usage

Uses

Used in Chemical and Pharmaceutical Research:
3,5-Dimethylpyrazin-2-ol is used as a research compound for investigating its potential role as a nucleobase residue of a primitive replicating molecule that preceded RNA. This application is crucial for understanding the early stages of molecular evolution and the development of life on Earth.
Used in the Study of Prebiotic Chemistry:
3,5-Dimethylpyrazin-2-ol is utilized in prebiotic chemistry to explore the formation and reactivity of simple organic compounds that may have played a role in the emergence of life. Its properties and interactions with other molecules can provide insights into the chemical processes that led to the formation of more complex biological molecules, such as nucleic acids and proteins.

InChI:InChI=1/C6H8N2O/c1-4-3-7-6(9)5(2)8-4/h3H,1-2H3,(H,7,9)

Upstream product

• 91678-81-8 2-amino-3,5-dimethyl pyrazine 
• 199983-58-9 1-hydroxy-3,5-dimethyl-1H-pyrazin-2-one 
• 38557-72-1 2-chloro-3,5-dimethylpyrazine 
• 86725-84-0 3-acetoxy-2,6-dimethylpyrazine 
• 80222-96-4 2-aminopropanamide hydrochloride 
• 78-98-8 2-oxopropanal 
• 31396-38-0 3,5-dimethyl-pyrazine-1-oxide 
• 412341-23-2 3,5-dimethyl-1-oxy-pyrazin-2-ylamine 
• 4726-84-5 alanine amide 

Downstream Products

• 91678-74-9 2-bromo-3,5-dimethyl-pyrazine 
• 92508-08-2 2-methoxy-3,5-dimethylpyrazine 
• 99969-02-5 2-iodo-3,5-dimethyl-pyrazine 

Relevant academic research and scientific papers

Isolation and identification of 2-methoxy-3,5-dimethylpyrazine, a potent musty compound from wine corks

The compound responsible for a fungal must taint evident in industry assessments of wine corks was identified as 2-methoxy-3,5- dimethylpyrazine. The identification was made on the basis of gas chromatography/odor analyses, collection of material using micropreparative techniques, determination of chemical properties of collected material, and comparison by gas chromatography/mass spectrometry with an authentic sample, synthesized from 2-hydroxy-3,5-dimethylpyrazine. 2-Methoxy-3,5-dimethylpyrazine is an extremely potent compound with an unpleasant, musty, moldy aroma and an aroma threshold in a white wine of 2.1 ng/L. While its contribution to the frequency and intensity of cork taint in bottled wine is yet to be established, it has been assessed by some wine industry personnel as second only to 2,4,6-trichloroanisole as a cause of cork taint in Australian wine.

PYRAZINES, PYRIMIDINES AND PYRIDAZINES USEFUL IN THE TREATMENT OF SENILE DEMENTIA

The present invention provides pyrazines, pyridazines or pyrimidines, or salts or prodrugs thereof, substituted on one of the ring carbon atoms thereof with a non-aromatic azacyclic or azabicyclic ring system; and independently substituted on each of the other ring carbon atoms with a substituent of low lipophilicity or a hydrocarbon substituent; which compounds stimulate central muscarinic acetylcholine receptors and therefore are useful in the treatment of neurological and mental illnesses.

Reactions of the Monoxides of 2,6-Disubstituted Pyrazines with Phosphoryl Chloride and Acetic Anhydride

The monoxides of 2,6-dimethyl- (1), 2,6-diphenyl- (2), and 2-methyl-6-phenylpyrazines (3) were subjected to the reactions with phosphoryl chloride and acetic anhydride.Some reactions of the chloropyrazines and hydroxypyrazines obtained thus were also inve