60190-80-9Relevant academic research and scientific papers
Fluoride-Mediated Dephosphonylation of α-Diazo-β-carbonyl Phosphonates
Phatake, Ravindra S.,Mullapudi, Venkannababu,Wakchaure, Vivek C.,Ramana, Chepuri V.
supporting information, p. 372 - 375 (2017/04/21)
The possibility of fluoride-mediated selective dephosphonylation of α-diazo-β-carbonyl phosphonates such as the Ohira-Bestmann reagent has been proposed and executed. The resulting α-diazocarbonyl intermediates undergo a (3 + 2)-cycloaddition at room temperature with conjugated olefins and benzynes. Interestingly, under the current conditions, the resulting cycloaddition products underwent either N-acylation (with excess α-diazo-β-carbonyl phosphonates) or Michael addition (with conjugated olefins).
Ir(III)-Catalyzed Synthesis of Isoquinoline N-Oxides from Aryloxime and α-Diazocarbonyl Compounds
Phatake, Ravindra S.,Patel, Pitambar,Ramana, Chepuri V.
supporting information, p. 292 - 295 (2016/02/03)
An efficient Ir(III)-catalyzed C-H activation and annulations of aryloxime with α-diazocarbonyl compounds has been developed for the synthesis of substituted isoquinoline N-oxides. The reaction proceeds under mild atmospheric conditions, without any external oxidants and releases N2 and H2O as the byproducts. In addition, synthetic applications of the N-oxide products have been established by performing further functionalization. An interesting dimeric iridacyclic complex allied through a bis-silver carboxylate bridge has been isolated that efficiently catalyzed the reaction.
Synthesis of α-diazo-β-keto esters, phosphonates and sulfones via acylbenzotriazole-mediated acylation of a diazomethyl anion
Pramanik, Mukund M. D.,Rastogi, Namrata
supporting information, p. 11567 - 11571 (2015/12/04)
We report a method for the synthesis of α-diazo-β-keto esters, phosphonates and sulfones via acylation of corresponding diazomethyl anions with N-acylbenzotriazoles. The N-o-amino-acylbenzotriazoles exhibited an unprecedented transphosphorylation reaction
A convenient reagent for aldehyde to alkyne homologation
Taber, Douglass F.,Bai, Sha,Guo, Peng-fei
experimental part, p. 6904 - 6906 (2009/04/10)
A convenient reagent for the one-carbon homologation of an aldehyde to the corresponding alkyne is reported. This reagent allows this conversion to conveniently be carried out on a large scale under ambient conditions.
