27491-70-9

Basic information

• Product Name: Nsc294729
• Synonyms: Nsc294729;Dimethyl Diazomethylphosphonate;DiMethylphosphonodiazoMethane;P-(DiazoMethyl)phosphonic Acid DiMethyl Ester;Seyferth-Gilbert Reagent
• CAS NO: 27491-70-9
• Molecular Formula: C₃H₇N₂O₃P
• Molecular Weight: 150.073041
• Product Categories: Miscellaneous Reagents
• Mol File: 27491-70-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: bp0.42 59°
• Appearance: /
• Refractive Index: nD25 1.4585
• Storage Temp.: -20°C Freezer, Under Inert Atmosphere
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• Stability: Moisture Sensitive
• CAS DataBase Reference: Nsc294729(CAS DataBase Reference)
• NIST Chemistry Reference: Nsc294729(27491-70-9)
• EPA Substance Registry System: Nsc294729(27491-70-9)

Safety Data

• Hazardous Substances Data: 27491-70-9(Hazardous Substances Data)

Usage

Chemical Properties

Yellow Oil

Uses

Different sources of media describe the Uses of 27491-70-9 differently. You can refer to the following data:
1. Reagent for one-carbon homologation of aldehydes and ketones to alkynes.
2. Seyferth-Gilbert Reagent

InChI:InChI=1/C3H8N2O3P/c1-7-9(6,8-2)3-5-4/h3-4H,1-2H3/q+1

Upstream product

• 4202-14-6 dimethyl (2-oxopropyl)phosphonate 
• 153650-87-4 dimethyl (3,3,3-trifluoro-2,2-dihydroxypropyl)phosphonate 
• 2158-14-7 4-acetamidobenzenesulfonyl azide 

Downstream Products

• 69762-72-7 <(Diethylamino)methylene>cyclohexane 
• 76886-47-0 cyclohexylidenemethyl-diisopropylamine 
• 54526-77-1 Allyloxymethylencyclohexan 
• 77419-64-8 4-[1-Allyloxy-meth-(E)-ylidene]-1-methyl-cyclohexene 
• 80907-80-8 (E)-(4,4-dibromo-2-methylbut-1,3-dien-1-yl)benzene 
• 25508-32-1 dimethyl <(methylthio)methyl>phosphonate 
• 61779-87-1 dimethyl bis(methylmercapto)methylphosphonate 
• 442899-67-4 4-[(1R,2R,3S,4S,5R,6S)-3-(tert-Butyl-dimethyl-silanyloxy)-6-methoxy-1,2,4-trimethyl-5-triethylsilanyloxy-oct-7-ynyloxymethyl]-1,2-dimethoxy-benzene 
• 416846-59-8 5-ethynyl-5-methyl-2-(2-methyl-[1,3]dioxolan-2-ylmethyl)-cyclohexa-1,3-dienecarboxylic acid methyl ester 
• 423118-16-5 (1'R,4R,6R)-4-[2-(tert-butyldiphenylsilanyloxy)-ethyl]-6-(1'-methylprop-2'-ynyl)-tetrahydropyran-2-one 
• 667419-32-1 (8R)-8-benzoyloxy-1-nonyne 
• 590366-68-0 C₃₅H₆₀O₂Si₂ 

Relevant articles and documents

Application of FSO2N3 in preparation of diazo reagent

The invention discloses application of FSO2N3 in preparation of a diazo reagent. The application comprises the following step: in the presence of alkali, FSO2N3 and acetone dimethyl phosphate as shown in a formula 2 are subjected to a reaction as shown in the specification, and a Bestmann-Ohira and/or Seyferth-Gilbert reagent is obtained. According to the application, the Seyferth-Gilbert reagent and/or the Bestmann-Ohira reagent can be obtained at a high yield in half an hour, the two mixed reagents generated in the reaction do not need to be separated, and the one-pot method is directly applied to the synthesis of the terminal alkyne compound. And/or like.