602-04-0Relevant articles and documents
Transformations of 6,7-difluoroquinoxaline with Indoles: Synthesis of Indole-Substituted 6,7-difluoroquinoxalines and Tris(indol-3-yl)methane Derivatives
Azev, Yu. A.,Ermakova,Ezhikova,Kodess,Berseneva,Kovalev
, (2017)
6,7-Difluoroquinoxaline (1) reacted with 1- and 2-methylindoles (2a and 2b) with heating in AcOH to give products from substitution of H in the heterocyclic fragment (3a and 3b) and tris(indol-3-yl)methane derivatives (4a and 4b).
Efficient and convenient method for the synthesis of symmetrical triindolylmethanes catalyzed by iodine
Zhang, Zhan-Hui,Lin, Jin
, p. 209 - 215 (2007)
Indoles reacted with triethyl orthoformate in the presence of a catalytic amount of iodine at room temperature to give the corresponding symmetrical triindolylmethanes (TIMs) in good to high yields. Copyright Taylor & Francis Group, LLC.
C-C bond cleavage: Metal-free-catalyzed reaction of Betti bases with various heterocycles under microwave irradiation
Deb, Mohit L.,Saikia, B.-Shriya,Borah, Kongkona,Baruah, Pranjal K.
supporting information, p. 1940 - 1946 (2016/11/25)
The reaction of Betti bases with various heterocycles in the presence of p-toluenesulphonic acid (PTSA) under microwave irradiation gives bis(heterocycle)methanes through benzyl transfer. The reaction proceeds via the cleavage of C-N bond followed by C-C
A short, novel, and practical synthesis of 3-alkenylated indoles
Kargar, Mojgan,Hekmatshoar, Rahim,Mostashari, Abdol Jalil
, p. 1743 - 1749 (2013/05/21)
Direct metal-free alkenylation of 2-methylindole via acid-mediated Michael addition-elimination reaction with ethoxymethylenemalononitrile or ethyl ethoxymethylenecyanoacetate affords 3-indolyl-2-cyanoacrylonitrile and ethyl 3-indolyl-2-cyanoacrylate. Behavior of 1H-indole is predictably different. Copyright Taylor & Francis Group, LLC.
