60211-80-5

Upstream product

• 955-83-9 2,5-diphenylfuran 
• 68-12-2 N,N-dimethyl-formamide 
• 64-17-5 ethanol 
• 55933-60-3 2-bromomethyl-1,4-diphenyl-but-2c-ene-1,4-dione 
• 13343-79-8 (E)-1,4-Diphenylbut-1-en-3-yne 
• 143536-16-7 1,4-Diphenyl-but-3-yne-1,2-diol 
• 55933-72-7 3-bromomethyl-2,5-diphenyl-furan 
• 15814-32-1 1,5-diphenylpenta-1,4-diyn-3-ol 
• 536-74-3 phenylacetylene 
• 2579-22-8 Phenylpropargyl aldehyde 
• 1613232-08-8 C₁₉H₁₆O₂ 
• 117552-49-5 1,5-diphenyl-pent-2ξ-en-4-yn-1-one 
• 1279101-13-1 (Z)-N-(2-bromo-3-oxo-3-phenylprop-1-enyl)-N-butyl-4-methylbenzenesulfonamide 
• 1279101-14-2 (Z)-2-bromo-3-(butylamino)-1-phenylprop-2-en-1-one 

Downstream Products

• 408330-99-4 (2,5-Diphenyl-[3]furyl)-methanol 
• 101600-61-7 2,5-diphenyl-furan-3-carbaldehyde-oxime 
• 247114-69-8 3-Chloromethyl-2,5-diphenylfuran 
• 500776-01-2 4-(2,5-diphenyl-[3]furylmethyl)-morpholine 

Relevant academic research and scientific papers

Rearrangement reaction synthesized 3-furan-carbaldehyde compound of silver catalytic epoxy compound and application of 3-furan-carbaldehyde compound

The invention discloses a rearrangement reaction synthesized 3-furan-carbaldehyde compound of a silver catalytic epoxy compound and application of the 3-furan-carbaldehyde compound. The 3-furan-carbaldehyde compound can be obtained with a 1-formyl-2-acete

Synthesis of 3-Formylfurans via a Silver(I)-Catalyzed Epoxide Ring-Opening/1,2-Acyl Migration/Cyclization Cascade

By the design of suitable starting materials, a silver(I)-catalyzed epoxide ring-opening/1,2-acyl migration/cyclization cascade has been developed, which allowed us to systematically prepare unsymmetrical 3-formylfurans. Various 3-formylfurans were prepared in good to excellent yields. In addition, the distinct fluorescence properties of 3-formylfurans in solution and the solid state are disclosed. (Figure presented.).

Synthesis of highly substituted 3-formylfurans by a gold(I)-catalyzed oxidation/1,2-alkynyl migration/cyclization cascade

3-Formylfuran derivatives are core structures of a variety of bioactive natural products. However, procedures for their preparation are still rare and generally inefficient in terms of atom economy: These methods require multiple steps or harsh reaction c

Synthesis of fully substituted 3-formyl-4-iodofurans via a gold(I)-catalyzed oxidation/1,2-alkynyl migration/cyclization/iodination cascade

A highly efficient gold(I)-catalyzed cascade reaction for the synthesis of fully substituted 3-formyl-4-iodofurans has been developed. Mechanistic investigations indicate a reaction pathway that involves a direct iodination reaction of the organogold intermediate via functionalization of the Au=C(sp2) bond, instead of a direct iodination of the 3-formylfurans.

Pd/Cu-catalyzed cascade Sonogashira coupling/cyclization reactions to highly substituted 3-formyl furans

An efficient palladium/copper-catalyzed approach to the synthesis of highly substituted 3-formyl furans from the reactions of readily available α-bromoenaminones with terminal alkynes has been developed. This methodology was realized by the cascade reactions of Sonogashira coupling and the subsequent intramolecular cyclization. The Royal Society of Chemistry 2011.

A brief synthesis of β-iodofurans

5-Endo-dig iodocyclisations of alk-3-yn-1,2-diols 4, followed by in situ dehydration, lead to good yields of β-iodofurans 5, which can subsequently be converted into a wide range of derivatives 6-13, using transition metal-catalysed coupling reactions or