60222-62-0Relevant academic research and scientific papers
Ligand-free Cu-catalyzed O-arylation of aliphatic diols
Zheng, Yufen,Zou, Wenxing,Luo, Laichun,Chen, Jiabei,Lin, Songwen,Sun, Qi
, p. 66104 - 66108 (2015)
Coupling reaction between aryl iodides and aliphatic diols was realized with a ligand-free copper catalyst under mild conditions. This method was successfully applied in the process of scale-up synthesis of medicinal candidate product EMB-3.
