602275-62-7

Upstream product

• 27829-72-7 ethyl (E)-hex-2-enoate 
• 17480-69-2 (S)-N-benzyl-1-phenylethylamine 

Downstream Products

• 1090902-97-8 (S)-3-(2-amino-phenylamino)-hexanoic acid ethyl ester 
• 1090902-96-7 (S)-3-(2-nitro-phenylamino)-hexanoic acid ethyl ester 
• 1090900-68-7 N-{(S)-3-[3-(1,4-dimethyl-1H-indol-3-ylmethyl)-2-oxo-2,3-dihydro-benzimidazol-1-yl]-hexanoyl}-benzenesulfonamide 
• 602275-70-7 (4S,1'S)-4-(N-α-methylbenzyl-N'-benzylamino)-1-trimethylsilyl-2-(trimethylsilylmethyl)heptan-2-ol 

Relevant academic research and scientific papers

A new asymmetric synthesis of 2,6-cis-disubstituted 4-methylenepiperidines: Total synthesis of (+)-alkaloid 241D and (+)-isosolenopsin A

A highly diastereoselective synthesis of 2,6-cis-disubstituted-4- methylenepiperidines based on a Mannich type intramolecular cyclization of an allylsilane on an iminium ion is described. The synthetic potential of this methodology is demonstrated by the

QUINAZOLINEDIONE CHYMASE INHIBITORS

Disclosed are small molecule inhibitors which are useful in treating various diseases and conditions involving Chymase.

BENZIMIDAZOLONE CHYMASE INHIBITORS

Disclosed are small molecule inhibitors which are useful in treating various diseases and conditions involving chymase.

A facile enantioselective synthesis of 2-(2-aminoethyl)allylsilanes, new synthons for piperidine synthesis

The synthesis of chiral (2-substituted-2-aminoethyl)allylsilanes by cerium mediated trimethylsilylmethylmagnesium chloride addition to the ester group of non racemic chiral β-aminoesters is described.