602275-67-2

Upstream product

• 13170-43-9 (trimethylsilyl)methylmagnesium chloride 
• 204587-98-4 (3R,1'R)-3-(N-α-methylbenzyl-N'-benzylamino)-butanoate 

Relevant academic research and scientific papers

A new asymmetric synthesis of 2,6-cis-disubstituted 4-methylenepiperidines: Total synthesis of (+)-alkaloid 241D and (+)-isosolenopsin A

A highly diastereoselective synthesis of 2,6-cis-disubstituted-4- methylenepiperidines based on a Mannich type intramolecular cyclization of an allylsilane on an iminium ion is described. The synthetic potential of this methodology is demonstrated by the

A facile enantioselective synthesis of 2-(2-aminoethyl)allylsilanes, new synthons for piperidine synthesis

The synthesis of chiral (2-substituted-2-aminoethyl)allylsilanes by cerium mediated trimethylsilylmethylmagnesium chloride addition to the ester group of non racemic chiral β-aminoesters is described.