60230-36-6

Basic information

• Product Name: 2,6-Difluorobenzenesulfonyl chloride
• Synonyms: 2,6-DIFLUOROBENZENE-1-SULFONYL CHLORIDE;2,6-DIFLUOROBENZENESULFONYL CHLORIDE;2,6-DIFLUOROBENZENESULPHONYL CHLORIDE;BENZENESULFONYL CHLORIDE, 2,6-DIFLUORO-;BUTTPARK 27\04-27;2,6-DIFLUOROBENZENESULFONYL CHLORIDE, 97;Benzenesulfonyl chloride, 2,6-difluoro- (9CI);2,6-Difluorobenzenesulphonyl chloride 98%
• CAS NO: 60230-36-6
• Molecular Formula: C₆H₃ClF₂O₂S
• Molecular Weight: 212.6
• EINECS: -0
• Product Categories: SULFONYLHALIDE;Fluorobenzene;Aromatic Halides (substituted);Benzenesulfonyl chloride;Miscellaneous;Benzenes;Organic Building Blocks;Sulfonyl Halides;Sulfur Compounds
• Mol File: 60230-36-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 210 °C(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 1.568 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.129mmHg at 25°C
• Refractive Index: n20/D 1.526(lit.)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Sensitive: Moisture Sensitive
• CAS DataBase Reference: 2,6-Difluorobenzenesulfonyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-Difluorobenzenesulfonyl chloride(60230-36-6)
• EPA Substance Registry System: 2,6-Difluorobenzenesulfonyl chloride(60230-36-6)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 3265 8/PG 2
• WGK Germany: 3
• HazardClass: 8
• PackingGroup: II
• Hazardous Substances Data: 60230-36-6(Hazardous Substances Data)

Usage

Chemical Properties

clear yellow liquid

Uses

2,6-Difluorobenzenesulfonyl chloride may be used in the synthesis of 2,6-difluorobenzenesulfonamide and benzoxathiazocine 1,1-dioxides core scaffolds.

General Description

2,6-Difluorobenzenesulfonyl chloride can be prepared by reacting difluorophenyllithium with sulfuryl chloride.

InChI:InChI=1/C6H3ClF2O2S/c7-12(10,11)6-4(8)2-1-3-5(6)9/h1-3H

Upstream product

• 372-18-9 1,3-Difluorobenzene 

Downstream Products

• 60230-37-7 2,6-difluorobenzene-1-sulfonamide 
• 952191-64-9 1-[(2,6-difluorophenyl)sulfonyl]-2-phenyl-1H-imidazole-4-carbaldehyde 
• 1423120-07-3 N-(3-(2-tert-butyl-5-(2-chloropyrimidin-4-yl)thiazol-4-yl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide-d₉ 
• 1423119-98-5 N-(3-(5-(2-aminopyrimidin-4-yl)-2-tert-butylthiazol-4-yl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide-d₉ 
• 1195768-23-0 N-{3-[5-(2-chloro-4-pyrimidinyl)-2-(1,1-dimethylethyl)-1 ,3-thiazol-4-yl]-2-fluorophenyl}-2,6-difluorobenzenesulfonamide 
• 1195768-20-7 N-(3-(2-(2-chloropyrimidin-4-yl)acetyl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide 
• 1195768-06-9 N-{3-[5-(2-amino-4-pyrimidinyl)-2-(1,1-dimethylethyl)-1,3-thiazol-4-yl]-2-fluorophenyl}-2,6-difluorobenzenesulfonamide methanesulfonic acid 
• 1195765-45-7 dabrafenib 
• 1415031-76-3 N-(4-(1-acetyl-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)-N-((2,6-difluorophenyl)sulfonyl)acetamide 
• 1415031-74-1 2,6-difluoro-N-(4-(5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)benzenesulfonamide 
• 1415031-64-9 (E)-2,6-difluoro-N-(4-(3-(4-methoxyphenyl)acryloyl)phenyl)benzenesulfonamide 
• 1415031-26-3 N-(4-(1-acetyl-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)-2,6-difluorobenzenesulfonamide 
• 1324745-11-0 N-(4-acetylphenyl)-2,6-difluorobenzenesulfonamide 
• 1022790-66-4 2-methyl-1-(methylsulfonyl)indoline 

Relevant articles and documents

Deuterated Benzene Sulfonamide Thiazole Compounds

Deuterated forms of N-{3-[5-(2-Amino-4-pyrimidinyl)-2-(1,1-dimethylethyl)-1,3-thiazol-4-yl]-2-fluorophenyl}-2,6-difluorobenzenesulfonamide and pharmaceutical compositions containing the same.

Insect growth regulators. Analogues of TH-6038 and TH-6040.

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