602302-21-6Relevant articles and documents
Diels-Alder reactions of phenylglycinol-derived bicyclic lactams. Enantiodivergent synthesis of cis-hydroisoquinolines
Casamitjana, Nuria,Amat, Mercedes,Llor, Nuria,Carreras, Marcal,Pujol, Xavier,Fernandez, M. Montserrat,Lopez, Virgina,Molins, Elies,Miravitlles, Carles,Bosch, Joan
, p. 2033 - 2039 (2007/10/03)
The diastereomeric phenylglycinol-derived unsaturated δ-lactams trans-3 and cis-3 react with dienes with exo facial diastereoselectivity to give the corresponding tricyclic adducts, which were ultimately converted to enantiomeric cis-hydroisoquinolines.