60234-82-4

Upstream product

• 60234-84-6 (2E,4E)-3-Methyl-5-p-tolyl-penta-2,4-dienoic acid ethyl ester 
• 60234-91-5 (2Z,4E)-3-Methyl-5-p-tolyl-penta-2,4-dienoic acid 
• 77144-26-4 (2E,4E)-3-Methyl-5-p-tolyl-penta-2,4-dienal 
• 77144-23-1 2-Hydroxy-2-methyl-4-(p-methylphenyl)-3-butene 
• 97585-04-1 ethyl (E)-3-(4-methylphenyl)acrylate 

Relevant academic research and scientific papers

A tentative descriptive modelling of chemical structure-biological activity relationships. Biological evaluation of a series of polyethylenic acids

48 new polyethylenic-malonic acids have been submitted to an antimicrobial and antifungal screening. After a suitable recoding, the experimental results were analyzed according to two mathematical multivariate analysis using a computer process i.e. Correspondence Factorial Analysis and Cluster Analysis. These methods allowed an accurate study of the structure of the system and a thorough investigation of the structure-activity-specificity relationships. On the other side, magnitude and/or specificity of the observed biological effects were related to structural features. These results should be useful in order to elaborate synthetic strategies.