60246-80-2Relevant academic research and scientific papers
Solvent-free synthesis of some 1,5-benzothiazepines and benzodiazepines and their antibacterial activity
Saini,Joshi,Joshi
, p. 2181 - 2190 (2008)
An efficient and convenient synthesis of 1, 5-benzothiazepines (3a-3f) and 1, 5-benzodiazepines (4a-4f) from chalcones (2a-2f) by the action of o-amino thiophenol and o-phenylenediamine in the presence of inorganic support is reported. These compounds are
A new route to 2,3-dihydro-1,5-benzothiazepines from nitrodisulfides and α,β-unsaturated ketones by Sml2
Chen,Zhong,Zhang
, p. 386 - 387 (2007/10/03)
Nitrodisulfides on treatment with Sml2 in anhydrous THF at room temperature lead to reactive intermediates, which are 'living' double-anions and react smoothly with α,β-unsaturated ketones to afford 2,3-dihydro-1,5-benzothiazepines in good yields under mild and neutral conditions.
