60278-93-5 Usage
Synonyms
Mephendioxan, Pimodendan
Chemical class
1,2-Propanediol derivative
Application
Treatment of congestive heart failure, veterinary medicine
Function
Inodilator (increases heart's ability to contract and dilates blood vessels)
Mechanism of action
Improved blood circulation
Additional properties
Potential anti-fibrotic and anti-inflammatory effects
Therapeutic potential
Cardiovascular and inflammatory conditions
Check Digit Verification of cas no
The CAS Registry Mumber 60278-93-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,2,7 and 8 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 60278-93:
(7*6)+(6*0)+(5*2)+(4*7)+(3*8)+(2*9)+(1*3)=125
125 % 10 = 5
So 60278-93-5 is a valid CAS Registry Number.
60278-93-5Relevant academic research and scientific papers
IMPROVED COMPOSITIONS AND METHODS FOR THE DELIVERY OF NUCLEIC ACIDS
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Paragraph 0225-0226, (2016/08/17)
The present invention provides compositions and methods for the delivery of therapeutic agents to cells. In particular, these include novel lipids and nucleic acid-lipid particles that provide efficient encapsulation of nucleic acids and efficient delivery of the encapsulated nucleic acid to cells in vivo. The compositions of the present invention are highly potent, thereby allowing effective knock-down of specific target protein at relatively low doses. In addition, the compositions and methods of the present invention are less toxic and provide a greater therapeutic index compared to compositions and methods previously known in the art.