60301-87-3 Usage
Uses
Used in the Synthesis of Chromogenic Substrates:
2-(N-HEXADECANOYLAMINO)-4-NITROPHENOL is used as a key component in the synthesis of a chromogenic substrate for assaying sphingomyelinase activity. This application is particularly relevant in the field of biochemistry and molecular biology, where the compound plays a crucial role in the detection and analysis of sphingomyelinase enzymes.
Used in the Pharmaceutical Industry:
In the pharmaceutical industry, 2-(N-HEXADECANOYLAMINO)-4-NITROPHENOL is used as an intermediate in the synthesis of various drugs and drug candidates. Its unique chemical properties make it a valuable building block for the development of new therapeutic agents.
Used in the Chemical Research Industry:
2-(N-HEXADECANOYLAMINO)-4-NITROPHENOL is also used in the chemical research industry as a reagent for various chemical reactions and experiments. Its off-white solid form and unique chemical structure make it an ideal candidate for research purposes, allowing scientists to explore its potential in the development of new compounds and materials.
Check Digit Verification of cas no
The CAS Registry Mumber 60301-87-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,3,0 and 1 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 60301-87:
(7*6)+(6*0)+(5*3)+(4*0)+(3*1)+(2*8)+(1*7)=83
83 % 10 = 3
So 60301-87-3 is a valid CAS Registry Number.
InChI:InChI=1/C22H36N2O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-22(26)23-20-18-19(24(27)28)16-17-21(20)25/h16-18,25H,2-15H2,1H3,(H,23,26)
60301-87-3Relevant academic research and scientific papers
Synthesis of 2-alkanoylamino-4-nitrophenyl phosphorylcholine-hydroxide
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, (2008/06/13)
A method for synthesizing a 2-alkanoylamino-4-nitrophenyl phosphorylcholine-hydroxide useful as a sphingomyelinase-specific chromogenic artificial substrate in the diagnostic testing for Niemann-Pick disease. The method comprises reacting 2-amino-4-nitrophenol with an alkanoyl halide to form the alkananilide; phosphorylating the alkali phenolate salt of the alkananilide with β-bromoethylphosphoryl dichloride to form a mixture of mono- and di-alkananilide phosphoric acid esters; recovering from the mixture the mono-alkananilide phosphoric acid ester and quaternizing it with trimethylamine; and treating the resulting quaternary salt with a mixture of weak acidic and weak basic ion exchange resins to convert it into the 2-alkanoylamino-4-nitrophenyl phosphoryl-choline-hydroxide.
