603039-46-9

Upstream product

• 189630-90-8 (4S,2E)-4-[(tert-butyldiphenylsilyl)oxy]pent-2-en-1-ol 
• 87696-33-1 (S)-2-(O-tert-butyldiphenylsilyloxy)propanal 
• 203387-35-3 (E)-(S)-4-(tert-butyl-diphenyl-silanyloxy)-pent-2-enoic acid ethyl ester 
• 107-30-2 chloromethyl methyl ether 
• 116223-21-3 (3R,4S)-4-[(t-butyldiphenylsilyl)oxy]pent-1-yn-3-ol 

Downstream Products

• 603039-50-5 C₃₇H₅₈O₇Si₂ 

Relevant academic research and scientific papers

Stereoselective synthesis of marine macrolide Aspergillide D

A formal stereoselective synthesis of the naturally occurring 16-membered macrolide aspergillide D is described. The origins of the chiral centers are ribose, lactic acid and the Sharpless asymmetric epoxidation protocol. The foremost reactions involved a

MACROCYCLIC COMPOUNDS USEFUL AS PHARMACEUTICALS

The present invention provides compounds having formula (I), and additionally provides methods for the synthesis thereof and methods for the use thereof in the treatment of various disorders including inflammatory or autoimmune disorders, and disorders involving malignancy or increased angiogenesis, wherein R1 -R11, t, X, Y, Z, and n are as defined herein.