603040-44-4

Upstream product

• 42890-76-6 (S)-1,2,4-butanetriol 
• 123-11-5 4-methoxy-benzaldehyde 
• 220524-51-6 2-[(S)-2-(4-Methoxy-phenyl)-[1,3]dioxolan-4-yl]-ethanol 
• 603040-43-3 [(S)-2-(4-Methoxy-phenyl)-[1,3]dioxolan-4-yl]-acetic acid methyl ester 

Downstream Products

• 603040-45-5 C₁₃H₁₆O₃ 
• 220524-50-5 (3S,1E,5Z)-3-para-methoxyphenylmethoxy-1-iodoundec-1,5-diene 
• 220524-47-0 (Z)-(S)-2-(4-Methoxy-benzyloxy)-dec-4-en-1-ol 
• 180722-67-2 2(S)-(4-methoxybenzyloxy)-4(Z)-decenal 
• 220524-52-7 (S)-2-(4-Methoxy-phenyl)-4-((Z)-oct-2-enyl)-[1,3]dioxolane 

Relevant academic research and scientific papers

MACROCYCLIC COMPOUNDS USEFUL AS PHARMACEUTICALS

The present invention provides compounds having formula (I), and additionally provides methods for the synthesis thereof and methods for the use thereof in the treatment of various disorders including inflammatory or autoimmune disorders, and disorders involving malignancy or increased angiogenesis, wherein R1 -R11, t, X, Y, Z, and n are as defined herein.

A chiron approach to the cyclopropyl lactone oxylipins

Enantiomerically pure key intermediates for the synthesis of constanolactones A and B and solandelactones A, B, E and F, the hydroxy- protected (3S,5Z)-undec-1-yn-5-en-3-ol and (3S,1E,5Z)-1-iodoundec-1,5-dien- 3-ol, have been obtained in nine steps starting from (S)-malic acid.

Total syntheses of (+)-castanospermine and (+)-6-epicastanospermine

A divergent synthetic route to (+)-castanospermine 1 and (+)-6-epicastanospermine 2 has been developed via phenylselenoamidation of trichloroacetimidate derived from allylic alcohol 7, and dihydroxylations of trans-olefins 14 and 18 to dispose the three c