603041-59-4

Upstream product

• 573692-58-7 methyl 6-amino-3-bromo-2-methylbenzoate 
• 76006-33-2 3-bromo-2-methylbenzoic acid 
• 99548-54-6 methyl 3-bromo-2-methylbenzoate 

Downstream Products

• 808127-80-2 Methyl 6-(acetyloxy)-3-bromo-2-methylbenzoate 
• 1616290-42-6 methyl 3-bromo-6-(2-hydroxyethoxy)-2-methylbenzoate 
• 1616290-44-8 methyl 3-bromo-2-methyl-6-(2-oxoethoxy)benzoate 
• 1616290-46-0 methyl 3-bromo-6-(2-{[(4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]amino}ethoxy)-2-methylbenzoate 
• 1616288-88-0 methyl 3-bromo-2-methyl-6-[2-(tetrahydro-2H-pyran-2-yloxy)ethoxy]benzoate 

Relevant academic research and scientific papers

WDR5-MYC INHIBITORS

Substituted N-phenyl sulfonamide compounds inhibit WDR5-MYC interactions, and the compounds and their pharmaceutical compositions are useful for treating disorders and conditions in a subject, such as cancer cell proliferation.

ARYL AND HETEROARYL FUSED LACTAMS

This invention relates to compounds of general formula (I) in which R1, R2, U, V, L, M, R5, m, X, Y and Z are as defined herein, and the pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising such compounds and salts, and to methods of using such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer.

Isoindolinone kinase inhibitors

Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.

ISOINDOLIN-1-ONE COMPOUNDS AS KINASE INHIBITORS

Compounds having the formula, (I) are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds and compositions containing the compounds.