603042-05-3Relevant articles and documents
Synthesis and biological evaluation of matrine derivatives as anti-hepatocellular cancer agents
Wu, Lichuan,Liu, Shuaibing,Wei, Jinrui,Li, Dong,Liu, Xu,Wang, Jianyi,Wang, Lisheng
, p. 4267 - 4271 (2016)
We delineate herein the synthesis and anti-cancer effects of 15 matrine derivatives. The in vitro growth inhibitory assays showed that most of the prepared compounds exhibited improved anti-proliferative activities towards cancer cells with IC50/sub
MACROCYCLIC COMPOUNDS USEFUL AS PHARMACEUTICALS
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Page/Page column 237, (2010/02/07)
The present invention provides compounds having formula (I), and additionally provides methods for the synthesis thereof and methods for the use thereof in the treatment of various disorders including inflammatory or autoimmune disorders, and disorders involving malignancy or increased angiogenesis, wherein R1 -R11, t, X, Y, Z, and n are as defined herein.