6038-12-6

Usage

Uses

Used in Organic Synthesis:
(E)-Cyclooct-1-enecarbaldehyde is used as a building block in organic synthesis for the creation of diverse organic molecules. Its cyclic structure and reactive aldehyde group make it a valuable component in the synthesis of complex organic compounds.
Used in Fragrance and Flavor Industry:
(E)-Cyclooct-1-enecarbaldehyde is used as a key component in the production of fragrance and flavor compounds. Its strong, fruity odor makes it an ideal candidate for enhancing the scent and taste of various products in this industry.
Used in Pharmaceutical Manufacturing:
(E)-Cyclooct-1-enecarbaldehyde is employed in the manufacturing of pharmaceuticals, where its unique chemical structure contributes to the development of new drugs and medicinal compounds.
Used in Agrochemicals Production:
(E)-Cyclooct-1-enecarbaldehyde is also utilized in the production of agrochemicals, where it can be a part of the synthesis process for creating pesticides, herbicides, and other agricultural chemicals.
Used as a Flavoring Agent in Food Products:
Due to its strong, fruity odor, (E)-Cyclooct-1-enecarbaldehyde is often used as a flavoring agent in the food industry to add a pleasant taste and aroma to various food products.
Safety Precautions:
It is important to handle (E)-Cyclooct-1-enecarbaldehyde with care, as it may be irritating to the skin, eyes, and respiratory tract. Proper safety measures should be taken during its use and storage to minimize potential health risks.

InChI:InChI=1/C9H14O/c10-8-9-6-4-2-1-3-5-7-9/h6,8H,1-5,7H2/b9-6+

Upstream product

• 201230-82-2 carbon monoxide 
• 502-49-8 cycloactanone 
• 68-12-2 N,N-dimethyl-formamide 
• 931-88-4 1,2-cyclooctene 
• 2567-85-3 cyclooctanone p-tolylsulfonylhydrazone 
• 18292-62-1 cyclooct-1c-enecarboxylic acid 
• 4103-11-1 1-bromocyclooctene 
• 931-88-4 cis-Cyclooctene 
• 57559-34-9 cyclooct-1-enecarbonitrile 
• 56900-55-1 1-Hydroxymethyl-cycloocten 

Downstream Products

• 1159912-86-3 C₂₁H₃₀ClFN₂ 
• 1644435-06-2 C₁₆H₂₀O₂ 

Relevant academic research and scientific papers

Method for preparing olefine aldehyde through catalytic oxidation of enol ether

The invention relates to the technical field of olefine aldehyde preparation, and provides a method for preparing olefine aldehyde through catalytic oxidation of enol ether. According to the invention, a palladium catalyst, a copper salt, a solvent and enol ether are mixed and subjected to a catalytic oxidation reaction to obtain olefine aldehyde. According to the method, the copper salt is used as the oxidizing agent, the mixed solvent of water and acetonitrile is used as the reaction solvent, and the volume ratio of water to acetonitrile in the mixed solvent is controlled to be (3-7): (3-7), so that the catalytic oxidation reaction can be smoothly carried out in the mixed solvent with a specific ratio, and the generation of palladium black precipitate can be avoided. The method provided by the invention has the advantages of simple steps, low reagent cost, no need of dangerous reagents, wide substrate adaptability and small catalyst dosage. Furthermore, octadecane mercaptan is added to promote the catalytic oxidation reaction, and when the dosage of the palladium catalyst is extremely low, the olefine aldehyde yield can be greatly increased by adding octadecane mercaptan.

Pd-Catalyzed Carbonylation of Vinyl Triflates to Afford α,β-Unsaturated Aldehydes, Esters, and Amides under Mild Conditions

An efficient and general protocol for the synthesis of α,β-unsaturated aldehydes, esters, and amides via carbonylation of vinyl triflates including derivatives of camphor, ketoisophorone, verbenone, and pulegone was developed. Crucial for these transformations is the use of a specific palladium catalyst containing a pyridyl-substituted dtbpx-type ligand. This procedure also allows for an easy access of dicarbonylated products from the corresponding ketones.

Exploring a pocket for polycycloaliphatic groups in the CXCR3 receptor with the aid of a modular synthetic strategy

A CXCR3 pocket capable of accommodating polycycloaliphatics was explored using a modular synthetic strategy. The systematic studies reveal that the tricyclic 2-adamantane and bicyclic (iso)bornyl group are efficiently recognized by CXCR3.

Palladium catalysts for the formylation of vinyl triflates to form α,β-unsaturated aldehydes

(Chemical Equation Presented) What a gas! Synthesis gas is the formylating agent in the efficient one-step title transformation promoted by a palladium catalyst with the bidentate ligand 1,2-bis(di-1-adamantylphosphinomethyl)benzene (see scheme). This method enables the conversion of six-to eight-membered-ring triflates into α,β-unsaturated aldehydes and the introduction of a formyl group into derivatives of elaborate natural compounds. Tf = trifluoromethanesulfonyl.

CYCLIC COMPOUNDS AND USES THEREOF

Compounds of general formula (1) or salts thereof, exhibiting preventive and therapeutic effects against HIV infectious diseases wherein R1 is an optionally substituted five- or six-membered ring group; X1 is a free valency or the like; W is a divalent group represented by, e. g., general formula (2) (wherein A and B are each an optionally substituted five-to seven-membered ring; E1 and E4 are each optionally substituted carbon or the like; E2 and E3 are each oxygen or the like; and a and b are each a single bond or a double bond); X2 is a divalent group constituting a straight chain moiety; Z1 is a divalent cyclic group or the like; Z2 is a free valency or the like; and R2 is optionally substituted amino or the like.