60395-85-9

Usage

Uses

Used in Chemical Synthesis Industry:
METHYL 4-(4-BROMOPHENYL)-2,4-DIOXOBUTANOATE is used as a chemical intermediate for the synthesis of various compounds in chemical reactions. Its unique structure and reactivity make it a valuable component in the creation of new molecules with specific properties and applications.
Used in Pharmaceutical Industry:
METHYL 4-(4-BROMOPHENYL)-2,4-DIOXOBUTANOATE is used as a building block in the development of pharmaceutical compounds. Its bromine atom and ester functionality can be exploited to create novel drug molecules with potential therapeutic effects.
Used in Research and Development:
METHYL 4-(4-BROMOPHENYL)-2,4-DIOXOBUTANOATE is utilized as a research compound to study its properties, reactivity, and potential applications in various fields. Scientists and researchers can explore its behavior under different conditions and interactions with other chemicals to discover new uses and applications.
Used in Environmental and Health Studies:
Due to its potential environmental and health effects, METHYL 4-(4-BROMOPHENYL)-2,4-DIOXOBUTANOATE is used in studies to understand its impact on the environment and human health. This knowledge can help in developing safer handling and storage methods, as well as guidelines for its use in various industries.

Upstream product

• 553-90-2 Dimethyl oxalate 
• 99-90-1 para-bromoacetophenone 

Downstream Products

• 887250-21-7 (Z)-3-(4-bromophenacylidene)-1-phenyl-1,2,3,4-tetrahydroquinoxalin-2-one 
• 84879-14-1 OC₆H₄OB(BrC₆H₄COCHCOCOOCH₃) 
• 84879-18-5 OC₆H₄CH₂OB(BrC₆H₄COCHCOCOOCH₃) 

Relevant academic research and scientific papers

ISOXAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF

The present invention generally relates to an isoxazole derivative, a preparation therefor, and a use thereof. In particular, the present invention provides a farnesoid X receptor (FXR) agonist compound, and a stereoisomer, a tautomer, a polymorph, a solvate (e.g., a hydrate), a pharmaceutically acceptable salt, an ester, a metabolite, and an N-oxide, and the chemically protected forms and prodrugs thereof. The present invention further provides a preparation method for the compound, an intermediate thereof, and a pharmaceutical composition and kit containing the same and used thereof for treating FXR-mediated diseases or conditions.

Non-peptide-based new class of platelet aggregation inhibitors: Design, synthesis, bioevaluation, SAR, and in silico studies

A series of 2-oxo-2-phenylethylidene linked 2-oxo-benzo[1,4]oxazine analogues 17a–x and 18a–o, incorporated with a variety of electron-withdrawing as well as electron-donating groups at ring A and ring C, were synthesized under greener conditions in excel

CYCLIC SULFAMIDE COMPOUNDS AND METHODS OF USING SAME

The present disclosure provides, in part, cyclic sulfamide compounds, and pharmaceutical compositions thereof, useful as modulators of Hepatitis B (HBV) core protein, and methods of treating Hepatitis B (HBV) infection.

A class of 1, 5 - diphenyl pyrazole - 3 - carboxylic acid compound and use thereof

The invention provides a 1, 5-diphenyl pyrazol-3-carboxylic acid compound and application thereof. The compound has a structure as shown in general formula I, wherein R1 is selected from -H, halogen, saturated alkyl of C1-C6, or -X1-R4; R2 is selected from H, halogen, saturated alkyl of C1-C6, or -X2-R5; R3 is selected from H, -NH2 or -NH-CO-Ph-(o, m, p)R6; R6 is selected from H, halogen, saturated alkyl of C1-C6, or -O-R7; X1 and X2 are respectively selected from O or S independently; R4, R5 and R7 are respectively selected from H, saturated alkyl of C1-C6, benzyl or phenyl substituted by saturated alkyl of C1-C6 independently. The compound provided by the invention simulates BH3-only and p53TAD protein alpha-helix at the same time, competitively binds and antagonize Mcl-1, Bcl-2 and MDM2 protein, and specifically causes tumor cell apoptosis, thereby realizing application as an anticancer compound. (general formula I).