60418-67-9Relevant academic research and scientific papers
All Non-Carbon B3NO2 Exotic Heterocycles: Synthesis, Dynamics, and Catalysis
Opie, Christopher R.,Noda, Hidetoshi,Shibasaki, Masakatsu,Kumagai, Naoya
supporting information, p. 4648 - 4653 (2019/03/17)
The B3NO2 six-membered heterocycle (1,3-dioxa-5-aza-2,4,6-triborinane=DATB), comprising three different non-carbon period 2 elements, has been recently demonstrated to be a powerful catalyst for dehydrative condensation of carboxylic acids and amines. The tedious synthesis of DATB, however, has significantly diminished its utility as a catalyst, and thus the inherent chemical properties of the ring system have remained virtually unexplored. Here, a general and facile synthetic strategy that harnesses a pyrimidine-containing scaffold for the reliable installation of boron atoms is disclosed, giving rise to a series of Pym-DATBs from inexpensive materials in a modular fashion. The identification of a soluble Pym-DATB derivative allowed for the investigation of the dynamic nature of the B3NO2 ring system, revealing differential ring-closing and -opening behaviors depending on the medium. Readily accessible Pym-DATBs proved their utility as efficient catalysts for dehydrative amidation with broad substrate scope and functional-group tolerance, offering a general and practical catalytic alternative to reagent-driven amidation.
Preparation method of fatty acid amide
-
Paragraph 0018, (2019/02/13)
The invention relates to a preparation method of fatty acid amide. The method includes: adding hydroxylamine hydrochloride, a transition metal, a phosphine ligand, olefin and a solvent into a high pressure reaction kettle in order, carrying out hydroamine
DETERMINATION OF ABSOLUTE CONFIGURATION OF THE DERIVATIVE FROM 2--propionic acid AND R-(+)-1-phenylethylamine BY 1H-NMR SPECTROSCOPY; USE OF SHIFT REAGENT WITH DIASTEREOISOMERIC AMIDES
Munari, Sergio De,Marazzi, Giuseppe,Forgione, Angelo,Longo, Antonio,Lombardi, Paolo
, p. 2273 - 2276 (2007/10/02)
The assignment of the S-(+), R-(-) absolute configuration of Indoprofene, an analgesic and anti-inflammatory drug, has been made via an NMR configurational correlation of diastereoisomeric phenylethylamides with the aid of Eu(fod)3.
