60451-75-4

Upstream product

• 19308-29-3 DL-erythro-α.β-Dibrom-β--propionsaeure-methylester 
• 871893-64-0 (Z)/(E)-ethyl 3-(4-methoxyphenyl)-2-bromo-2-propenoate 
• 57038-78-5 methyl 2-bromo-3-(4-methoxyphenyl)acrylate 
• 123098-26-0 ethyl 2-bromo-3-(4-methoxyphenyl)-2(Z)-propenoate 

Downstream Products

• 67722-41-2 (Z)-4-(4-methoxybenzylidene)-2-(pyridin-4-yl)-4,5-dihydro-1H-imidazol-5-one 
• 58486-86-5 2-phenyl-5-[1-(4-methoxyphenyl)-meth-(Z)-ylidene]-3,5-dihydro-imidazol-4-one 
• 1234334-11-2 (Z)-4-(4-methoxybenzylidene)-2-propyl-4,5-dihydro-1H-imidazol-5-one 
• 1234334-12-3 (Z)-2-cyclopropyl-4-(4-methoxybenzylidene)-4,5-dihydro-1H-imidazol-5-one 
• 57038-78-5 methyl 2-bromo-3-(4-methoxyphenyl)prop-2(Z)-enoate 
• 1376213-91-0 (Z)-methyl 4-bromo-3-hydroxy-5-(4-methoxyphenyl)pent-4-enoate 
• 1376214-04-8 (Z)-methyl 4-bromo-5-(4-methoxyphenyl)-3-oxopent-4-enoate 
• 1263037-08-6 (Z)-3-benzyl-5-(4-methoxybenzylidene)oxazolidine-2,4-dione 

Relevant academic research and scientific papers

Cu/CuxOyNPs architectured COF: a recyclable catalyst for the synthesis of oxazolidinedioneviaatmospheric cyclizative CO2utilization

The present study describes the favourable construction of a crystalline covalent organic framework (COF) with exceptional surface area, tunable pore size and huge CO2capture efficiency to facilitate a novel multicomponent cyclization by introducing CO2into extremely reactive organic skeletons. In the presence of a catalytic Cu/CuxOyNP-loaded COF, several 2-bromo-3-alkylacrylic acids combined with several amine derivatives and CO2(0.1 MPa) are converted to the desired oxazolidinediones in excellent yields (up to 96%) under alkali-free conditions and ambient temperature.

Chemical fixation of carbon dioxide by copper catalyzed multicomponent reactions for oxazolidinedione syntheses

The quest to reduce greenhouse gases has triggered the development of new chemical fixation of carbon dioxide. Given the importance of CO2 based transformation chemistry, we demonstrate the fixation of CO2 for oxazolidinedione synthesis via a novel multicomponent synthesis. In the presence of a catalytic amount of Cu2O, various 2-bromo-3-phenylacrylic acid derivatives reacted with CO2 and amines are transformed to the corresponding oxazolidinedione derivatives in high yields. This journal is

Ru-catalyzed highly chemo- and enantioselective hydrogenation of γ-halo-γ,δ-unsaturated-β-keto esters under neutral conditions

Finely-tuned ruthenium-catalyzed highly chemoselective and enantioselective hydrogenation of γ-halo-γ,δ-unsaturated-β-keto esters at the carbonyl group was achieved under neutral reaction conditions (ee up to 97%). Both olefin and alkenyl halogen moieties, which are labile under hydrogenation conditions, remained untouched during the reaction.

Simple and efficient copper-catalyzed approach to 2,4-disubstituted imidazolones

(Figure Presented) Some imidazolone derivatives are biological and pharmaceutical active molecules and the chromophores of the fluorescent proteins. In this communication, a simple and efficient approach to 4-arylidene-2-alkyl-4,5-dihydro-1H-imidazol-5-ones (2,4-disubstituted imidazolones) has been developed, and the protocol uses readily available 2-bromo-3-alkylacrylic acids and amidines as the starting materials without addition of any ligand or additive. The reactions were performed under mild conditions. Therefore, the present method will be of wide application in organic chemistry and medicinal chemistry.