60455-40-5 Usage
Uses
Used in Scientific Research:
(1,1,1’,1’-tetradeuterodiethyl)amine is used as a research compound for studying the effects of deuterium substitution on chemical reactions and molecular interactions. The presence of deuterium can alter the kinetic properties of the molecule, making it a valuable tool for understanding reaction mechanisms and improving the efficiency of chemical processes.
Used in NMR Spectroscopy:
In the field of nuclear magnetic resonance (NMR) spectroscopy, (1,1,1’,1’-tetradeuterodiethyl)amine is used as a labeled compound to enhance the resolution and sensitivity of the NMR signals. The deuterium atoms can provide additional information about the molecular structure and dynamics, which is crucial for the accurate interpretation of the NMR data.
Used in Chemical Synthesis:
(1,1,1’,1’-tetradeuterodiethyl)amine can be employed as a starting material or an intermediate in the synthesis of various deuterated organic compounds. The deuterium-labeled products can have different chemical and physical properties compared to their non-deuterated counterparts, which can be beneficial for specific applications, such as in pharmaceuticals or materials science.
Used in Isotope Tracing:
In environmental and biological studies, (1,1,1’,1’-tetradeuterodiethyl)amine can be used as an isotope tracer to track the fate and transport of the compound in various systems. The deuterium label allows for the differentiation between the labeled compound and other similar compounds, providing valuable insights into the processes occurring in the system.
Used in Drug Development:
(1,1,1’,1’-tetradeuterodiethyl)amine can be utilized in the development of deuterated drugs, which may exhibit improved pharmacokinetic and pharmacodynamic properties compared to their non-deuterated versions. The deuterium substitution can lead to enhanced stability, reduced metabolism, and improved bioavailability, potentially resulting in more effective therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 60455-40-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,4,5 and 5 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 60455-40:
(7*6)+(6*0)+(5*4)+(4*5)+(3*5)+(2*4)+(1*0)=105
105 % 10 = 5
So 60455-40-5 is a valid CAS Registry Number.
60455-40-5Relevant academic research and scientific papers
PHOTOCHEMICAL REACTIONS OF ARENECARBONITRILES WITH ALIPHATIC AMINES. 1. EFFECT OF ARENE STRUCTURE ON AMINYL VS. alpha -AMINOALKYL RADICAL FORMATION.
Lewis,Zebrowski,Correa
, p. 187 - 193 (2007/10/02)
The photochemical reactions of several singlet arenecarbonitriles with aliphatic amines have been investigated. The reactions of 9-phenanthrenecarbonitrile with diethylamaine and its N- and alpha -C deuterated derivatives result in exclusive N-H atom transfer to yield the diethylaminyl and 9-cyano-9,10-dihydrophenanthren-9-yl radicals in benzene solution. Increased solvent polarity results in the formation of both diethylaminyl and 1-(ethylamino)ethyl radical. Similar results are obtained with 9-anthracenecarbonitrile. The competition between aminyl vs. alpha -aminoalkyl radical formation in this and other reactions is reviewed. Aminyl radical formation is characteristic of relatively nonpolar heteroexcimers in which hydrogen bonding may favor N-H transfer. Pure charge-transfer exciplexes, like alkoxyl radicals, yield predominantly the thermodynamically more stable alpha -aminoalkyl radical.
Quantification of lidocaine and several metabolites utilizing chemical ionization mass spectrometry and stable isotope labeling
Nelson,Garland,Breck,Trager
, p. 1180 - 1190 (2007/10/05)
Quantification of the suspected metabolites of lidocaine in humans was carried out using the direct insertion probe and chemical-ionization mass spectrometry. Deuterated analogs of the metabolites of lidocaine were added to serial human plasma and urine s
