60456-20-4Relevant academic research and scientific papers
Alkoxide-catalyzed addition of alkyl carbonates across alkynes-stereoselective synthesis of (: E)-β-alkoxyacrylates
Wendling, Timo,Risto, Eugen,Erb, Benjamin,Goo?en, Lukas J.
supporting information, p. 643 - 646 (2017/08/15)
Dialkyl carbonates were found to regio- and stereoselectively add to terminal alkynes in the presence of catalytic amounts of potassium methoxide. Various synthetically meaningful aryl- and heteroaryl-substituted (E)-β-alkoxyacrylates were thus obtained i
Stereoselective formation of (E)-β-alkoxy acrylates from fischer carbene complexes and chelated amino acid ester enolates
Chaudhuri, Rupsha,Kazmaier, Uli
, p. 693 - 695 (2014/04/03)
Chelated amino acid ester enolates react with alkyl Fischer carbene complexes via nucleophilic attack on the electrophilic carbene center. Subsequent elimination of the metal fragment and trifluoroacetamide results in the formation of β-alkoxy-α,β-unsaturated esters in a highly E-stereoselective fashion. Georg Thieme Verlag Stuttgart. New York.
