604809-72-5Relevant academic research and scientific papers
Side-chain-to-tail thiolactone peptide inhibitors of the staphylococcal quorum-sensing system
Scott, R. John,Lian, Lu-Yun,Muharram, S. Hanna,Cockayne, Alan,Wood, Stewart J.,Bycroft, Barrie W.,Williams, Paul,Chan, Weng C.
, p. 2449 - 2453 (2003)
The expression of many staphylococcal virulence factors are regulated by the agr locus via a two-component signal transduction system (TCSTS), which is activated in response to a secreted autoinducer peptide (AIP). By exploiting the unique chemical archit
