60521-91-7

Upstream product

• 108-24-7 acetic anhydride 
• 105052-56-0 methyl (S)-2-amino-3-(4-aminophenyl)propanoate 
• 36097-42-4 2(S)-acetylamino-3-(4-amino-phenyl)-propionic acid methyl ester 
• 17363-92-7 N-acetyl-4-nitro-L-phenylalanine 
• 36097-39-9 (S)-methyl 2-acetamido-3-(4-nitrophenyl)propanoate 

Downstream Products

• 942218-75-9 C₁₄H₁₇ClN₂O₄ 
• 864238-42-6 D,L-4-Acetamido-N-acetyl-3-nitrophenylalanine methyl ester 
• 864238-27-7 Fmoc-Phe(4-NH₂-3-NO₂)-OH 

Relevant academic research and scientific papers

COMPOSITIONS CONTAINING, METHODS INVOLVING, AND USES OF NON-NATURAL AMINO ACIDS AND POLYPEPTIDES

Disclosed herein are non-natural amino acids and polypeptides that include at least one non-natural amino acid, and methods for making such non-natural amino acids and polypeptides. The non-natural amino acids, by themselves or as a part of a polypeptide, can include a wide range of possible functionalities, but typical have at least one aromatic amine group. Also disclosed herein are non-natural amino acid polypeptides that are further modified post-translationally, methods for effecting such modifications, and methods for purifying such polypeptides. Typically, the modified non-natural amino acid polypeptides include at least one alkylated amine group. Further disclosed are methods for using such non-natural amino acid polypeptides and modified non-natural amino acid polypeptides, including therapeutic, diagnostic, and other biotechnology uses.

Direct solid-phase synthesis of quinoxaline-containing peptides

The solid-phase synthesis of a series of model dipeptides containing various 3-(quinoxalin-6-yl)alanine analogues is described. The method involves formation of a quinoxaline heterocycle by condensation between an α-dicarbonyl compound and a β-(3,4-diamin

Antihypertensive compositions containing an aryl-substituted alanine azo and an arylhydrazino-propionic acid

Novel pharmaceutical compositions are disclosed. The compositions comprise an aryl substituted alanine and a substituted phenyl hydrazino propionic acid. The compositions are useful for treating hypertension.

Amino acids and esters thereof useful as antihypertensive agents

A compound of the formula STR1 possesses antihypertensive activity. Also provided are methods for the preparation of the compounds as well as pharmaceutical formulations and methods for their use as antihypertensive agents.