60530-20-3Relevant academic research and scientific papers
Iodine-Mediated Direct Generation of o-Quinone Methides at Room Temperature: A Facile Protocol for the Synthesis of ortho-Hydroxybenzyl Thioethers
Basha, R. Sidick,Chen, Chia-Wei,Reddy, Daggula Mallikarjuna,Lee, Chin-Fa
, p. 2475 - 2483 (2018/05/29)
An iodine-mediated preparation of ortho-quinone methides (o-QMs) from ortho-hydroxybenzyl alcohols by a C?O bond scission strategy is described. The in situ generated o-QMs were then employed for C?S bond formation by thio-Michael addition of thiols to provide the ortho-hydroxybenzyl thioethers (o-HBT) in moderate to excellent yields.
Antioxidant-Based Inhibitors of Leukotriene Biosynthesis. The Discovery of 6--1-propen-3-yl>-2,3-dihydro-5-benzofuranol, a Potent Topical Antiinflammatory Agent
Hammond, Milton L.,Zambias, Robert A.,Chang, Michael N.,Jensen, Norman P.,McDonald, John,et al.
, p. 909 - 918 (2007/10/02)
The leukotrienes, metabolites of arachidonic acid produced through the action of the enzyme 5-lipoxygenase, are important mediators of immediate hypersensitivity and inflammation.Among the variety of diseases in which the leukotrienes may play a symptomat
