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6055-19-2

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6055-19-2 Usage

Chemical Properties

White to Off-White Solid

Uses

Different sources of media describe the Uses of 6055-19-2 differently. You can refer to the following data:
1. It is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity. This substance is listed as a known human carcinogen.
2. antineoplastic, alkylating agent
3. alkylating agent in cancer therapy
4. An immunosuppressive, cytotoxic apoptosis inducer.
5. Cyclophosphamide monohydrate is used to treat cancers, autoimmune disorders and AL amyloidosis. It is a nitrogen mustard alkylating agent and reacts with deoxyribonucleic acid (DNA) to get its alkylated derivative. It is also involved in cancer research as a tool that induces apoptosis in tumor cells.

Definition

ChEBI: The monohydrate of cyclophosphamide.

General Description

Fine white crystalline powder with a slightly bitter taste. Little or no odor.

Air & Water Reactions

Water soluble. Sensitive to moisture and light. Aqueous solutions may be kept for a few hours above room temperature, but hydrolysis occurs at temperatures above 86°F. Cyclophosphamide monohydrate undergoes both specific acid and specific base catalysis at extreme pHs. Spontaneous hydrolysis in aqueous solutions.

Reactivity Profile

Polymerization can occur at temperatures > 120° F. Cyclophosphamide monohydrate reacts with strong oxidizing agents, strong acids and strong bases. Benzyl alcohol increases rate of hydrolysis.

Fire Hazard

Cyclophosphamide monohydrate is probably combustible.

Biochem/physiol Actions

Cyclophosphamide is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity.

Safety Profile

Confirmed human carcinogen. Poison by ingestion and intravenous routes. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of Cl-, PO,, and NOx.

Check Digit Verification of cas no

The CAS Registry Mumber 6055-19-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,0,5 and 5 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 6055-19:
(6*6)+(5*0)+(4*5)+(3*5)+(2*1)+(1*9)=82
82 % 10 = 2
So 6055-19-2 is a valid CAS Registry Number.
InChI:InChI=1/C7H15Cl2N2O2P.H2O/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2/t14-;/m1./s1

6055-19-2 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail
  • TCI America

  • (C2236)  Cyclophosphamide Monohydrate  >98.0%(N)

  • 6055-19-2

  • 5g

  • 690.00CNY

  • Detail
  • TCI America

  • (C2236)  Cyclophosphamide Monohydrate  >98.0%(N)

  • 6055-19-2

  • 25g

  • 2,390.00CNY

  • Detail
  • Alfa Aesar

  • (L11508)  Cyclophosphamide monohydrate, 97+%   

  • 6055-19-2

  • 1g

  • 306.0CNY

  • Detail
  • Alfa Aesar

  • (L11508)  Cyclophosphamide monohydrate, 97+%   

  • 6055-19-2

  • 5g

  • 912.0CNY

  • Detail
  • Sigma

  • (C0768)  Cyclophosphamidemonohydrate  bulk package

  • 6055-19-2

  • C0768-1G

  • 565.11CNY

  • Detail
  • Sigma

  • (C0768)  Cyclophosphamidemonohydrate  bulk package

  • 6055-19-2

  • C0768-5G

  • 2,004.21CNY

  • Detail
  • Sigma

  • (C0768)  Cyclophosphamidemonohydrate  bulk package

  • 6055-19-2

  • C0768-10G

  • 3,410.55CNY

  • Detail
  • Sigma

  • (C0768)  Cyclophosphamidemonohydrate  bulk package

  • 6055-19-2

  • C0768-25G

  • 7,692.75CNY

  • Detail

6055-19-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name cyclophosphamide hydrate

1.2 Other means of identification

Product number -
Other names Cyclophosphamide monohydrate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6055-19-2 SDS

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