60555-55-7

Basic information

• Product Name: 2-[2-(2-thienyl)ethyl]-1H-Isoindole-1,3(2H)-dione
• Synonyms: 2-[2-(2-thienyl)ethyl]-1H-Isoindole-1,3(2H)-dione
• CAS NO: 60555-55-7
• Molecular Formula: C₁₄H₁₁NO₂S
• Molecular Weight: 257.30764
• Mol File: 60555-55-7.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-[2-(2-thienyl)ethyl]-1H-Isoindole-1,3(2H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[2-(2-thienyl)ethyl]-1H-Isoindole-1,3(2H)-dione(60555-55-7)
• EPA Substance Registry System: 2-[2-(2-thienyl)ethyl]-1H-Isoindole-1,3(2H)-dione(60555-55-7)

Safety Data

• Hazardous Substances Data: 60555-55-7(Hazardous Substances Data)

Usage

Chemical compound

2-[2-(2-thienyl)ethyl]-1H-Isoindole-1,3(2H)-dione

Class

Isoindole-1,3(2H)-diones

Moiety

Thienyl

Potential applications

Medicinal chemistry, drug discovery

Properties

Unique structure, potential biological activities

Uses

Building block for synthesis of pharmaceutical compounds

Further investigation

Required for specific uses and properties through research and testing.

Upstream product

• 30433-91-1 [2-(2-thyenyl)ethyl]amine 
• 85-44-9 phthalic anhydride 
• 1126518-66-8 (E)-2-(2-(2-thienyl)vinyl)isoindoline-1,3-dione 
• 201230-82-2 carbon monoxide 
• 610-97-9 o-iodo-methyl-benzoic acid 
• 136918-14-4 phthalimide 
• 22509-74-6 N-ethoxycarbonylphthalimide 

Downstream Products

• 30433-91-1 [2-(2-thyenyl)ethyl]amine 
• 188471-64-9 3-Hydroxy-3-phenyl-2-(2-thiophen-2-yl-ethyl)-2,3-dihydro-isoindol-1-one 

Relevant articles and documents

Palladium-catalyzed one-step synthesis of isoindole-1,3-diones by carbonylative cyclization of o-halobenzoates and primary amines

(Chemical Equation Presented) The palladium-catalyzed aminocarbonylation of o-halobenzoates produces 2-substituted isoindole-1,3-diones in good yields. This methodology provides a good one-step approach to this important class of heterocycles and tolerates a variety of functional groups, including methoxy, alcohol, ketone, and nitro groups.

Acyliminium ion cyclizations: Synthesis of thieno[2',3':3,4]pyrrolo[2,1-a]isoindolone and benzo[a]thieno[2,3(3,2 or 3,4)-g]indolizinones

N-acyliminium cyclizations onto thiophene to give thieno[2',3':3,4]pyrrolo[2,1-a]isoindolone (2b) and benzo[a]thieno[2,3(3,2 or 3,4)-g]indolizinones (12a-c) were studied.

Process for the preparation of 2-(2-thienyl)-ethylamine and derivatives thereof

This invention relates to a process for the preparation of compounds of the formula: STR1 in which R1 and R2 may represent hydrogen or a lower alkyl or optionally substituted phenyl radical, comprising aminating a derivative of the formula: STR2 in which R3 is an optionnally substituted alkyl, aryl or aralkyl group, and R1 and R2 are as defined for formula (I).