60562-16-5

Usage

Uses

1. Used in Biological Research:
1,2-Dimyristoyl-sn-glycerol is used as a research tool for studying the role of diacylglycerol in cellular signaling and the activation of protein kinase C (PKC). Its weak second messenger properties make it a valuable compound for understanding the mechanisms of PKC activation and its downstream effects on cellular processes.
2. Used in Pharmaceutical Development:
1,2-Dimyristoyl-sn-glycerol is used as a starting point for the development of new pharmaceutical compounds targeting protein kinase C (PKC). By understanding the interactions between DAGs and PKC, researchers can design more effective drugs for various therapeutic applications, such as cancer treatment or other diseases where PKC plays a significant role.
3. Used in Analytical Chemistry:
1,2-Dimyristoyl-sn-glycerol can be used as a reference compound in analytical chemistry for the identification and quantification of diacylglycerols in biological samples. Its unique structure and properties make it a useful standard for developing and validating analytical methods for DAG analysis.
4. Used in Lipid Chemistry:
1,2-Dimyristoyl-sn-glycerol is used in lipid chemistry for studying the properties and functions of diacylglycerols in biological systems. Its saturated nature and specific fatty acid composition allow researchers to investigate the effects of lipid structure on membrane properties, enzyme activity, and other cellular processes.
5. Used in Cosmetics and Personal Care:
1,2-Dimyristoyl-sn-glycerol may be used in the cosmetics and personal care industry as an ingredient in various formulations, such as creams, lotions, and other skincare products. Its emollient properties and ability to form stable emulsions can contribute to the texture, feel, and efficacy of these products.

Upstream product

• 73083-33-7 1-(tetradecanoyl)-3-O-benzyl-sn-glycerol 
• 112-64-1 tetradecanoyl chloride 
• 544-63-8 n-tetradecanoic acid 

Downstream Products

• 96802-16-3 Tetradecanoic acid 2-((2-chloro-phenoxy)-{2-[6-oxo-2-(9-phenyl-9H-xanthen-9-ylamino)-1,6-dihydro-purin-9-ylmethoxy]-ethoxy}-phosphoryloxy)-1-tetradecanoyloxymethyl-ethyl ester 
• 905911-96-8 2-O-benzyl-1,3-bis[(1,2-di-O-myristoyl-sn-glycero-3)-phosphoryl]glycerol di(2-cyanoethyl) ester 
• 96812-94-1 Tetradecanoic acid 2-(hydroxy-{2-[6-oxo-2-(9-phenyl-9H-xanthen-9-ylamino)-1,6-dihydro-purin-9-ylmethoxy]-ethoxy}-phosphoryloxy)-1-tetradecanoyloxymethyl-ethyl ester; compound with triethyl-amine 
• 96802-13-0 Tetradecanoic acid 2-[[2-(2-amino-6-oxo-1,6-dihydro-purin-9-ylmethoxy)-ethoxy]-(2-chloro-phenoxy)-phosphoryloxy]-1-tetradecanoyloxymethyl-ethyl ester 
• 628722-33-8 Tetradecanoic acid (R)-2-[{2-benzyloxy-3-[((R)-2,3-bis-tetradecanoyloxy-propoxy)-(2-chloro-phenoxy)-phosphoryloxy]-propoxy}-(2-chloro-phenoxy)-phosphoryloxy]-1-tetradecanoyloxymethyl-ethyl ester 
• 628722-39-4 2-O-benzyl-1,3-bis-(1,2-O-dimyristoyl-sn-glycero-3-phosphoryl)glycerol dimethyl ether 
• 998-07-2 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine 
• 18194-24-6 dimyristoylphosphatidylcholine 

Relevant academic research and scientific papers

The Chiral Target of Daptomycin Is the 2R,2′S Stereoisomer of Phosphatidylglycerol

Daptomycin (dap) is an important antibiotic that interacts with the bacterial membrane lipid phosphatidylglycerol (PG) in a calcium-dependent manner. The enantiomer of dap (ent-dap) was synthesized and was found to be 85-fold less active than dap against

Synthesis and structural characterization of three unique helicobacter pylori a-cholesteryl phosphatidyl glucosides

Steryl glycosides produced by bacteria play important biological roles in the evasion and modulation of host immunity. Step-economical syntheses of three cholesteryl-6-Ophosphatidyl-α-d-glucopyranosides (αCPG) unique to Helicobacter pylori have been achie