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N,N-Dimethyl-3-phenyl-3-hydroxypropylamine, commonly known as tramadol, is a synthetic opioid analgesic primarily used for the management of moderate to severe pain. It functions by binding to mu-opioid receptors in the central nervous system, thereby inhibiting the transmission of pain signals. Additionally, tramadol influences the reuptake of serotonin and norepinephrine, which further contributes to its pain-relieving effects. It is typically administered orally in both immediate-release and extended-release forms and is sometimes combined with acetaminophen for enhanced efficacy. Tramadol is recognized for its lower risk of dependency and respiratory depression compared to other opioids, although it still has the potential for abuse and misuse. Common side effects include dizziness, drowsiness, constipation, and nausea, and it may interact with other medications and substances.

60577-28-8

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60577-28-8 Usage

Uses

Used in Pain Management:
N,N-Dimethyl-3-phenyl-3-hydroxypropylamine is used as an analgesic agent for the treatment of moderate to severe pain. It is effective due to its action on mu-opioid receptors and its influence on the reuptake of serotonin and norepinephrine, which collectively contribute to its pain-relieving properties.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, N,N-Dimethyl-3-phenyl-3-hydroxypropylamine is utilized in the formulation of various pain relief medications. It is often combined with other analgesics, such as acetaminophen, to provide a more comprehensive approach to pain management while minimizing the risk of side effects associated with higher doses of opioids.
Used in Research and Development:
N,N-Dimethyl-3-phenyl-3-hydroxypropylamine serves as a subject of research and development in the field of pharmaceuticals, with ongoing studies aimed at understanding its mechanisms of action, improving its efficacy, and reducing the potential for abuse and misuse. This research is crucial for the development of safer and more effective pain management therapies.

Check Digit Verification of cas no

The CAS Registry Mumber 60577-28-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,5,7 and 7 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 60577-28:
(7*6)+(6*0)+(5*5)+(4*7)+(3*7)+(2*2)+(1*8)=128
128 % 10 = 8
So 60577-28-8 is a valid CAS Registry Number.
InChI:InChI=1/C11H17NO/c1-12(2)11(9-13)8-10-6-4-3-5-7-10/h3-7,11,13H,8-9H2,1-2H3

60577-28-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name N,N-Dimethyl-3-phenyl-3-hydroxypropylamine

1.2 Other means of identification

Product number -
Other names 2-dimethylamino-3-phenyl-1-propanol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:60577-28-8 SDS

60577-28-8Relevant academic research and scientific papers

Basic amine esters or oleic acid and their use as anti-inflammatory or immunobodulatory agents

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Page/Page column 10-11, (2010/11/28)

This invention is directed to compounds of the following formula (I): wherein R is either: wherein R1 and R2 are as defined in the specification; the use of these compounds for treating inflammatory disorders; and pharmaceutical comp

Benzazepine and benzothiazepine derivatives

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, (2008/06/13)

Vasodilating activity is exhibited by compounds having the formula STR1 wherein X can be --S--or --CH2 --; and R2 is STR2 depending upon the definition of X.

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