60585-83-3Relevant academic research and scientific papers
Convergent approaches to saudin intermediates
Cravero, Raquel M.,Gonzalez-Sierra, Manuel,Labadie, Guillermo R.
, p. 2741 - 2753 (2003)
Different convergent approaches to the highly oxygenated sesquiterpene natural product saudin (1), has been investigated. Our strategy has included a Michael addition and aldol condensation reaction as key steps. During the synthetic development, we have found serious steric hindrance when an α-Me-substituted alkyl vinyl ketone was used. Such steric hindrance has been overcome by synthesizing the vinyl ketone 16 through an anionic fragmentation, which was carefully studied. Finally, the intermediate 18 has been synthesized in a one-pot reaction from the vinyl ketone 16 and has been cyclized to obtain the promising tricyclic intermediate 20.
Structure of Gas Phase +. Ions
Flammang, Robert,Meyrant, Philippe,Maquestiau, Andre,Kingston, Eric E.,Beynon, John H.
, p. 253 - 257 (1985)
Charge-stripping spectra have been used to differentiate ionized cyclopentadiene from its acyclic isomers.The minimum amounts of translational energy lost during the charge-stripping processes and the relative charge-stripping efficiencies, which are also structurally important parameters, have been measured for these ionic species. +. ions, formed by dissociative ionization of various precursors in the ion source are found, usually, to be a mixture of cyclic and acyclic ions.In contrast, +. ions, derived from the dissociation of metastable molecular ions from a series of organic compounds, have the cyclopentadienyl structure.This structure was confirmed by collision-induced dissociation of ions formed in the first field-free region of a triple sector mass spectrometer.
